Lipid metabolism is an important and complex biochemical process involved in the storage
of energy and maintenance of normal biological functions. Leucine, a branched amino acid …

Impaired muscle recovery (size and strength) following a disuse period commonly occurs in
older adults. Many of these individuals are not able to adequately exercise due to pain and …

Branched‐chain amino acids (BCAA) are essential in the diet and promote several vital cell
responses which may have benefits for health and athletic performance, as well as disease …

BACKGROUND The lack of specific predictors for type-2 diabetes mellitus (T2DM) severely
impacts early intervention/prevention efforts. Elevated branched-chain amino acids (BCAAs …

Elevated circulating branched-chain amino acids (BCAA) such as leucine have been
consistently correlated with increasing severity of insulin resistance across numerous …

Among the branched-chain amino acids, leucine and isoleucine have been well studied for
their roles in improving mitochondrial function and reducing oxidative stress. However, role …

Population data have consistently demonstrated a correlation between circulating branched-
chain amino acids (BCAA) and insulin resistance. Most recently valine catabolite, 3 …

Purpose Branched-chain amino acids (BCAA) have been shown to enhance several cellular
signaling pathways including protein synthesis and mitochondrial biogenesis, yet population …

Branched-chain amino acids (BCAA) are correlated with severity of insulin resistance, which
may partially result from mitochondrial dysfunction. Mitochondrial dysfunction is also …

Higher intramyocellular lipid (IMCL) deposition in skeletal muscle is commonly observed in
patients with obesity, resulting in mitochondrial damage. Palmitic acid, a saturated fatty acid …