[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers

CH Lin, CH Chen, ZC Lin, JY Fang - Journal of food and drug analysis, 2017 - Elsevier
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

Solid lipid nanoparticles for enhanced oral absorption: A review

E Salah, MM Abouelfetouh, Y Pan, D Chen… - colloids and surfaces B …, 2020 - Elsevier
Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Solid lipid nanoparticles and nanostructured lipid carriers in oral cancer drug delivery

S Nasirizadeh, B Malaekeh-Nikouei - Journal of Drug Delivery Science and …, 2020 - Elsevier
Most cancer disease can be treated by the parenteral anticancer delivery method. The
intravenous route takes the wholly bioavailable, accurate dose of the drug immediately to …

Layer-by-layer assembly of liposomal nanoparticles with PEGylated polyelectrolytes enhances systemic delivery of multiple anticancer drugs

T Ramasamy, ZS Haidar, TH Tran, JY Choi, JH Jeong… - Acta Biomaterialia, 2014 - Elsevier
Abstract Layer-by-layer (LbL)-engineered nanoparticles (NPs) are a promising group of
therapeutic carriers used in an increasing number of biomedical applications. The present …

Lipid-based nanoformulations in the treatment of neurological disorders

FH Pottoo, S Sharma, MN Javed, MA Barkat… - Drug Metabolism …, 2020 - Taylor & Francis
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …

Development of a graphene oxide nanocarrier for dual-drug chemo-phototherapy to overcome drug resistance in cancer

TH Tran, HT Nguyen, TT Pham, JY Choi… - … applied materials & …, 2015 - ACS Publications
Despite tremendous progress in chemotherapy, drug resistance remains a major challenge
for anticancer treatment. The combinations of chemo-photothermal and chemo-chemo …

Hyaluronic acid-coated solid lipid nanoparticles for targeted delivery of vorinostat to CD44 overexpressing cancer cells

TH Tran, JY Choi, T Ramasamy, DH Truong… - Carbohydrate …, 2014 - Elsevier
Hyaluronic acid (HA)-decorated solid lipid nanoparticles (SLNs) were developed for tumor-
targeted delivery of vorinostat (VRS), a histone deacetylase inhibitor. HA, a naturally …

Layer-by-layer coated lipid–polymer hybrid nanoparticles designed for use in anticancer drug delivery

T Ramasamy, TH Tran, JY Choi, HJ Cho, JH Kim… - Carbohydrate …, 2014 - Elsevier
Polyelectrolyte multilayers created via sequential adsorption of complimentary materials
may be useful in the delivery of small molecules such as anti-cancer drugs. In this study …