Immunotherapy for glioblastoma: the promise of combination strategies

M Bausart, V Préat, A Malfanti - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The
current standard of care involves surgical resection (if possible) followed by concomitant …

Macrophages in recurrent glioblastoma as a prognostic factor in the synergistic system of the tumor microenvironment

N Montemurro, B Pahwa, A Tayal, A Shukla… - Neurology …, 2023 - mdpi.com
Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous
system in adults. Ever more recent papers are focusing on understanding the role of the …

Glioblastoma microenvironment and cellular interactions

CB Crivii, AB Boșca, CS Melincovici, AM Constantin… - Cancers, 2022 - mdpi.com
Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Friends with benefits: chemokines, glioblastoma-associated microglia/macrophages, and tumor microenvironment

E Codrici, ID Popescu, C Tanase, AM Enciu - International journal of …, 2022 - mdpi.com
Glioma is the most common primary intracranial tumor and has the greatest prevalence of all
brain tumors. Treatment resistance and tumor recurrence in GBM are mostly explained by …

Advances in chemokine signaling pathways as therapeutic targets in glioblastoma

RM Urbantat, P Vajkoczy, S Brandenburg - Cancers, 2021 - mdpi.com
Simple Summary Chemokine signaling is crucial for tumorigenesis, proliferation,
angiogenesis, tumor progression and metastasis in glioblastoma. Furthermore, chemokines …

Surgical outcome and molecular pattern characterization of recurrent glioblastoma multiforme: A single-center retrospective series

N Montemurro, GN Fanelli, C Scatena, V Ortenzi… - Clinical Neurology and …, 2021 - Elsevier
Objective Despite recent advances in diagnosis and treatment of the disease, the prognosis
of patients with glioblastoma multiforme (GBM) remains poor. While the value of molecular …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma

Y Li, Y Wang, L Gao, Y Tan, J Cai, Z Ye… - Journal of …, 2022 - Springer
Background Glioblastoma (GBM) is the most common and fatal primary tumor in the central
nervous system (CNS). Due to the existence of blood–brain barrier (BBB), most therapeutics …

Old and new systemic immune-inflammation indexes are associated with overall survival of glioblastoma patients treated with radio-chemotherapy

F Pasqualetti, C Giampietro, N Montemurro, N Giannini… - Genes, 2022 - mdpi.com
Background. Systemic immunity and inflammation indexes (SI) derived from blood cells
have gained increasing attention in clinical oncology as potential biomarkers that are …

Converging mechanisms of epileptogenesis and their insight in glioblastoma

KE Hills, K Kostarelos, RC Wykes - Frontiers in molecular …, 2022 - frontiersin.org
Glioblastoma (GBM) is the most common and advanced form of primary malignant tumor
occurring in the adult central nervous system, and it is frequently associated with epilepsy, a …