Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

Ageing and mesenchymal stem cells derived exosomes: molecular insight and challenges

M Ahmadi, J Rezaie - Cell Biochemistry and Function, 2021 - Wiley Online Library
Ageing induces a great risk factor that participates in progressing various degenerative
diseases morbidities. The main characteristic of ageing is the failure in maintaining …

The systematic effect of mesenchymal stem cell therapy in critical COVID-19 patients: a prospective double controlled trial

G Adas, Z Çukurova, KK Yasar, R Yilmaz… - Cell …, 2021 - journals.sagepub.com
The aim of this clinical trial was to control the cytokine storm by administering mesenchymal
stem cells (MSCs) to critically-ill COVID-19 patients, to evaluate the healing effect, and to …

Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation

K Abdolmohammadi, T Mahmoudi, M Alimohammadi… - Life Sciences, 2023 - Elsevier
Acute inflammatory diseases such as acute colitis, kidney injury, liver failure, lung injury,
myocardial infarction, pancreatitis, septic shock, and spinal cord injury are significant causes …

[HTML][HTML] Two faces of the coin: Minireview for dissecting the role of reactive oxygen species in stem cell potency and lineage commitment

A Nugud, D Sandeep, AT El-Serafi - Journal of advanced research, 2018 - Elsevier
Reactive oxygen species (ROS) are produced as by-products of several intracellular
metabolic pathways and are reduced to more stable molecules by several protective …

Trends and recent developments in pharmacotherapy of acute pancreatitis

J Hey-Hadavi, P Velisetty, S Mhatre - Postgraduate Medicine, 2023 - Taylor & Francis
Acute pancreatitis (AP), a complex inflammatory disease of the pancreas, is associated with
increased morbidity and mortality. Currently, no specific therapies are approved for its …

Mesenchymal stromal cell therapy for pancreatitis: Progress and challenges

Z Ma, J Zhou, T Yang, W Xie, G Song… - Medicinal Research …, 2021 - Wiley Online Library
Pancreatitis is a common gastrointestinal disease with no effective therapeutic options,
particularly for cases of severe acute and chronic pancreatitis (CP). Mesenchymal stromal …

Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated …

Y Zhao, J Yan, AP Li, ZL Zhang, ZR Li, KJ Guo… - Toxicology Letters, 2019 - Elsevier
This study focused on the effect of bone marrow mesenchymal stem cells (BMSCs) on the
repair of rat liver injury induced by Cr (VI). Twenty-four Wistar rats were randomly divided …

Mesenchymal stem cells as new therapeutic approach for diabetes and pancreatic disorders

A Scuteri, M Monfrini - International journal of molecular sciences, 2018 - mdpi.com
Diabetes is a worldwide disease which actually includes different disorders related to
glucose metabolism. According to different epidemiological studies, patients affected by …

[HTML][HTML] Effect of hypoxia preconditioned adipose-derived mesenchymal stem cell conditioned medium on cerulein-induced acute pancreatitis in mice

K Abdolmohammadi, T Mahmoudi… - Advanced …, 2020 - ncbi.nlm.nih.gov
Purpose: Acute pancreatitis (AP) is an inflammatory disorder distinguished by tissue injury
and inflammation of the pancreas. Using paracrine potential of mesenchymal stem cells …