The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Recent advances and future directions in clinical management of head and neck squamous cell carcinoma

J Muzaffar, S Bari, K Kirtane, CH Chung - Cancers, 2021 - mdpi.com
Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

Transoral robotic surgery vs. radiotherapy for management of oropharyngeal squamous cell carcinoma–a systematic review of the literature

DH Yeh, S Tam, K Fung, SD MacNeil, J Yoo… - European Journal of …, 2015 - Elsevier
Background Intensity-modulated radiation therapy (IMRT) with or without concurrent
chemotherapy is widely utilized for the treatment of oropharyngeal squamous cell carcinoma …

Transoral endoscopic head and neck surgery and its role within the multidisciplinary treatment paradigm of oropharynx cancer: robotics, lasers, and clinical trials

FC Holsinger, RL Ferris - Journal of Clinical Oncology, 2015 - ascopubs.org
Transoral endoscopic head and neck surgery is a new approach for the treatment of
oropharyngeal tumors. Using either a robotic system and/or laser, surgeons gain access …

Current perspectives on recurrent HPV-mediated oropharyngeal cancer

T Guo, SY Kang, EEW Cohen - Frontiers in Oncology, 2022 - frontiersin.org
In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …

Surgical salvage improves overall survival for patients with HPV‐positive and HPV‐negative recurrent locoregional and distant metastatic oropharyngeal cancer

T Guo, JR Qualliotine, PK Ha, JA Califano, Y Kim… - Cancer, 2015 - Wiley Online Library
BACKGROUND Human papillomavirus (HPV) tumor status and surgical salvage are
associated with improved prognosis for patients with recurrent oropharyngeal squamous cell …

Comparison of survival after transoral robotic surgery vs nonrobotic surgery in patients with early-stage oropharyngeal squamous cell carcinoma

AT Nguyen, M Luu, J Mallen-St Clair, AC Mita… - JAMA …, 2020 - jamanetwork.com
Importance Transoral robotic surgery has been widely adopted since approval by the US
Food and Drug Administration in December 2009, despite limited comparative data …

Review of RM-1929 near-infrared photoimmunotherapy clinical efficacy for unresectable and/or recurrent head and neck squamous cell carcinoma

NL Miyazaki, A Furusawa, PL Choyke, H Kobayashi - Cancers, 2023 - mdpi.com
Simple Summary RM-1929 near-infrared photoimmunotherapy (NIR-PIT) is an emerging
treatment that is currently being investigated under a world-wide Phase III clinical trial and …

Transoral robotic surgery and intensity-modulated radiotherapy in the treatment of the oropharyngeal carcinoma: a systematic review and meta-analysis

A De Virgilio, A Costantino, G Mercante… - European Archives of …, 2021 - Springer
Purpose To perform a meta-analysis evaluating trans-oral robotic surgery (TORS), and
intensity-modulated radiation therapy (IMRT) in the treatment of oropharyngeal squamous …

Current role of surgery in the management of oropharyngeal cancer

W Golusiński, E Golusińska-Kardach - Frontiers in oncology, 2019 - frontiersin.org
In the last few decades, the surgical treatment of oropharyngeal squamous cell carcinoma
(OPSCC) has undergone enormous changes. Until the 1990s, open surgery was the primary …