The OPEP protein model: from single molecules, amyloid formation, crowding and hydrodynamics to DNA/RNA systems
F Sterpone, S Melchionna, P Tuffery… - Chemical Society …, 2014 - pubs.rsc.org
The OPEP coarse-grained protein model has been applied to a wide range of applications
since its first release 15 years ago. The model, which combines energetic and structural …
since its first release 15 years ago. The model, which combines energetic and structural …
Plant phosphoinositide-dependent phospholipases C: variations around a canonical theme
I Pokotylo, Y Kolesnikov, V Kravets, A Zachowski… - Biochimie, 2014 - Elsevier
Phosphoinositide-specific phospholipase C (PI-PLC) cleaves, in a Ca 2+-dependent
manner, phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P 2) into diacylglycerol (DAG) and …
manner, phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P 2) into diacylglycerol (DAG) and …
Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis
The biosynthesis of UDP-N-acetylmuramic acid (UDP-MurNAc) by reduction of UDP-N-
acetylglucosamine-enolpyruvate (UDP-GlcNAc-EP) in an NADPH and FAD-dependent …
acetylglucosamine-enolpyruvate (UDP-GlcNAc-EP) in an NADPH and FAD-dependent …
Structure-based mutational studies of O-acetylserine sulfhydrylase reveal the reason for the loss of cysteine synthase complex formation in Brucella abortus
S Dharavath, I Raj, S Gourinath - Biochemical Journal, 2017 - portlandpress.com
Cysteine biosynthesis takes place via a two-step pathway in bacteria, fungi, plants and
protozoan parasites, but not in humans, and hence, the machinery of cysteine biosynthesis …
protozoan parasites, but not in humans, and hence, the machinery of cysteine biosynthesis …
Investigation of the calcium-induced activation of the bacteriophage T5 peptidoglycan hydrolase promoting host cell lysis
AO Kovalenko, SV Chernyshov, VP Kutyshenko… - Metallomics, 2019 - academic.oup.com
Peptidoglycan hydrolase of bacteriophage T5 (EndoT5) is a Ca2+-dependent l-alanyl-d-
glutamate peptidase, although the mode of Ca2+ binding and its physiological significance …
glutamate peptidase, although the mode of Ca2+ binding and its physiological significance …
Secondary Structure Preferences of Mn2+ Binding Sites in Bacterial Proteins
TA Khrustaleva - Advances in Bioinformatics, 2014 - Wiley Online Library
3D structures of proteins with coordinated Mn2+ ions from bacteria with low, average, and
high genomic GC‐content have been analyzed (149 PDB files were used). Major Mn2+ …
high genomic GC‐content have been analyzed (149 PDB files were used). Major Mn2+ …
Prediction of structure of human WNT-CRD (FZD) complex for computational drug repurposing
The observed genetic alterations of various extracellular and intracellular WNT (Wingless,
Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene …
Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene …
Do It Yourself—Dock It Yourself: General Concepts and Practical Considerations for Beginners to Start Molecular Ligand–Target Docking Simulations
T Scior - Molecular Docking for Computer-Aided Drug Design, 2021 - Elsevier
Medicinal chemists without practical molecular modeling experience are invited to practice
simple docking simulations of small organic molecules into biomolecular targets. These …
simple docking simulations of small organic molecules into biomolecular targets. These …
On the roles of calcium and zinc ions in the formation of a catalytically active form of the metalloenzyme, l-alanyl-d-glutamate peptidase of the bacteriophage T5 …
VP Kutyshenko, GV Mikoulinskaia… - International Journal of …, 2020 - Elsevier
Structural consequences of the binding of metal ions (regulatory Ca 2+ and catalytic Zn 2+)
to the metalloenzyme l-alanyl-d-glutamate peptidase of the bacteriophage T5 (Endo T5) and …
to the metalloenzyme l-alanyl-d-glutamate peptidase of the bacteriophage T5 (Endo T5) and …
Effect of Wnt3a on Keratinocytes Utilizing in Vitro and Bioinformatics Analysis
JS Nam, C Chakraborty, AR Sharma, Y Her… - International journal of …, 2014 - mdpi.com
Wingless-type (Wnt) signaling proteins participate in various cell developmental processes.
A suppressive role of Wnt5a on keratinocyte growth has already been observed. However …
A suppressive role of Wnt5a on keratinocyte growth has already been observed. However …