[HTML][HTML] Machine perfusion of thoracic organs

D Van Raemdonck, F Rega, S Rex… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
This article summarizes recent knowledge and clinical advances in machine perfusion (MP)
of thoracic organs. MP of thoracic organs has gained much attention during the last decade …

Current status and future potential of ex vivo lung perfusion in clinical lung transplantation

AL Zhou, EL Larson, JM Ruck, JS Ha… - Artificial …, 2023 - Wiley Online Library
Lung transplantation is accepted as a well‐established and effective treatment for patients
with end‐stage lung disease. While the number of candidates added to the waitlist continues …

[HTML][HTML] Strategies to prolong homeostasis of ex vivo perfused lungs

M Takahashi, HYA Cheung, T Watanabe… - The Journal of Thoracic …, 2021 - Elsevier
Objectives Ex vivo lung perfusion provides an innovative method to assess and repair donor
lungs. The current Toronto ex vivo lung perfusion protocol can reliably and reproducibly …

Porcine lungs perfused with three different flows using the 8-h open-atrium cellular ex vivo lung perfusion technique

SN Buttar, H Møller-Sørensen, M Perch… - … in bioengineering and …, 2024 - frontiersin.org
The number of lung transplantations is limited due to the shortage of donor lungs fulfilling
the standard criteria. The ex vivo lung perfusion (EVLP) technique provides the ability of re …

Lung transplantation after ex vivo lung perfusion in two Scandinavian centres

T Nilsson, A Wallinder, I Henriksen… - European Journal of …, 2019 - academic.oup.com
OBJECTIVES We reviewed our combined clinical outcome in patients who underwent lung
transplantation after ex vivo lung perfusion (EVLP) and compared it to the contemporary …

National utilization, trends, and lung transplant outcomes of static versus portable ex vivo lung perfusion platforms

AL Zhou, JM Ruck, AJ Casillan, EL Larson… - The Journal of Thoracic …, 2024 - Elsevier
Background This study compared utilization and outcomes of the 2 widely utilized ex vivo
lung perfusion (EVLP) platforms in the United States: a static platform and a portable …

Early pulmonary function and mid‐term outcome in lung transplantation after ex‐vivo lung perfusion – a single‐center, retrospective, observational, cohort study

J Fumagalli, L Rosso, F Gori, LC Morlacchi… - Transplant …, 2020 - Wiley Online Library
Outcomes after transplantation of lungs (LuTX) treated with ex‐vivo lung perfusion (EVLP)
are debated. In a single‐center 8 years of retrospective analysis, we compared: donors' and …

Ex vivo lung perfusion: current achievements and future directions

NK Prasad, C Pasrija, T Talaie, AS Krupnick… - …, 2021 - journals.lww.com
There is a severe shortage in the availability of donor organs for lung transplantation. Novel
strategies are needed to optimize usage of available organs to address the growing global …

Endothelial glycocalyx shedding occurs during ex vivo lung perfusion: a pilot study

TM Sladden, S Yerkovich, D Wall, M Tan… - Journal of …, 2019 - Wiley Online Library
Background. Damage to the endothelium has been established as a key pathological
process in lung transplantation and ex vivo lung perfusion (EVLP), a new technology that …

Transplant suitability of rejected human donor lungs with prolonged cold ischemia time in low-flow acellular and high-flow cellular ex vivo lung perfusion systems

T Okamoto, D Wheeler, CF Farver, KR McCurry - Transplantation, 2019 - journals.lww.com
Background. Ex vivo lung perfusion (EVLP) has the potential to increase the number of
donor lungs available for lung transplantation (LTx). While the current maximum cold …