CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against pathogens and malignancies, and the molecular processes that lead to TRM cell formation …
Owing to their capacity to rapidly spread across the population, airborne pathogens represent a significant risk to global health. Indeed, several of the past major global …
FM Behr, L Parga-Vidal, NAM Kragten… - Nature …, 2020 - nature.com
Tissue-resident memory CD8+ T cells (TRM cells) are crucial in protecting against reinvading pathogens, but the impact of reinfection on their tissue confinement and …
Immunotherapy is now the standard of care for advanced hepatocellular carcinoma (HCC), yet many patients fail to respond. A major unmet goal is the boosting of T-cells with both …
Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) …
Tissue-resident memory (TRM) CD8+ T cells are largely derived from recently activated effector T cells, but the mechanisms that control the extent of TRM differentiation within …
C Friedrich, RLRE Taggenbrock… - Nature …, 2021 - nature.com
Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation, and early immunity against infection. It is unclear how ILCs acquire effector function and whether these …
YH Lin, HG Duong, AE Limary, ES Kim, P Hsu… - Immunity, 2023 - cell.com
Tissue-resident memory CD8+ T (T RM) cells are a subset of memory T cells that play a critical role in limiting early pathogen spread and controlling infection. T RM cells exhibit …
L Parga-Vidal, FM Behr, NAM Kragten, B Nota… - Science …, 2021 - science.org
Tissue-resident memory CD8+ T cells (TRM) constitute a noncirculating memory T cell subset that provides early protection against reinfection. However, how TRM arise from …