Effects of pre-analytical processes on blood samples used in metabolomics studies
Every day, analytical and bio-analytical chemists make sustained efforts to improve the
sensitivity, specificity, robustness, and reproducibility of their methods. Especially in targeted …
sensitivity, specificity, robustness, and reproducibility of their methods. Especially in targeted …
The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings
Well preserved frozen biospecimens are ideal for evaluating the genome, transcriptome,
and proteome. While papers reviewing individual aspects of frozen biospecimens are …
and proteome. While papers reviewing individual aspects of frozen biospecimens are …
Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism
Background Long-COVID is characterized by prolonged, diffuse symptoms months after
acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking …
acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking …
[HTML][HTML] Metabolomics profiling of critically ill coronavirus disease 2019 patients: identification of diagnostic and prognostic biomarkers
Objectives: Coronavirus disease 2019 continues to spread rapidly with high mortality. We
performed metabolomics profiling of critically ill coronavirus disease 2019 patients to …
performed metabolomics profiling of critically ill coronavirus disease 2019 patients to …
[HTML][HTML] Endothelial injury and glycocalyx degradation in critically ill coronavirus disease 2019 patients: implications for microvascular platelet aggregation
Objectives: Coronavirus disease 2019 is caused by the novel severe acute respiratory
syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular …
syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular …
What proportion of Salmonella Typhi cases are detected by blood culture? A systematic literature review
V Mogasale, E Ramani, VV Mogasale… - Annals of clinical …, 2016 - Springer
Blood culture is often used in definitive diagnosis of typhoid fever while, bone marrow
culture has a greater sensitivity and considered reference standard. The sensitivity of blood …
culture has a greater sensitivity and considered reference standard. The sensitivity of blood …
Inflammation profiling of critically ill coronavirus disease 2019 patients
Objectives: Coronavirus disease 2019 is caused by severe acute respiratory syndrome-
coronavirus-2 infection to which there is no community immunity. Patients admitted to ICUs …
coronavirus-2 infection to which there is no community immunity. Patients admitted to ICUs …
[HTML][HTML] Biomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID‐19: a single‐center prospective longitudinal study
Background Immunothrombosis and coagulopathy in the lung microvasculature may lead to
lung injury and disease progression in coronavirus disease 2019 (COVID‐19). We aim to …
lung injury and disease progression in coronavirus disease 2019 (COVID‐19). We aim to …
Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA
MA Kerachian, M Azghandi, S Mozaffari-Jovin… - Clinical …, 2021 - Springer
Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …
[HTML][HTML] Alpha-fetoprotein analysis
OO Adigun, SNS Yarrarapu, M Zubair… - StatPearls …, 2024 - ncbi.nlm.nih.gov
Human α-fetoprotein (AFP) is a tumor-associated fetal mammalian glycoprotein involved in
ontogenic and oncogenic growth.[1] This tumor marker is encoded by the AFP gene on …
ontogenic and oncogenic growth.[1] This tumor marker is encoded by the AFP gene on …