Osteomyelitis remains one of the greatest risks in orthopaedic surgery. Although many
organisms are linked to skeletal infections, Staphylococcus aureus remains the most …

Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Osteomyelitis is a devastating disease caused by microbial infection of bone. While the
frequency of infection following elective orthopedic surgery is low, rates of reinfection are …

Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Chronic implant-related bone infections are a major problem in orthopedic and trauma-
related surgery with severe consequences for the affected patients. As antibiotic resistance …

Although Staphylococcus aureus osteomyelitis is considered to be incurable, the major
bacterial reservoir in live cortical bone has remained unknown. In addition to biofilm bacteria …

Abstract Purpose of Review Staphylococcus aureus is the primary pathogen responsible for
osteomyelitis, which remains a major healthcare burden. To understand its dominance, here …

Abstract Purpose of Review The incidence of complications from prosthetic joint infection
(PJI) is increasing, and treatment failure remains high. We review the current literature with a …

Staphylococcus aureus is an important human and livestock pathogen that is well-protected
against environmental insults by a thick cell wall. Accordingly, the wall is a major target of …

Orthopaedic and trauma device-related infection (ODRI) remains one of the major
complications in modern trauma and orthopaedic surgery. Despite best practice in medical …