The involvement of post-translational modifications in regulating the development and progression of Alzheimer's disease

PP Guan, P Wang - Molecular Neurobiology, 2023 - Springer
Post-translational modifications (PTMs) have been recently reported to be involved in the
development and progression of Alzheimer's disease (AD). In detail, PTMs include …

Glycation regulates phase separation by attenuating electrostatic interactions and increasing hydrophobic interactions

YY Luo, JJ Hu, YJ Lim, PY He, YM Li - New Journal of Chemistry, 2023 - pubs.rsc.org
Liquid–liquid phase separation (LLPS) was recently discovered to be a ubiquitous method
of substance organization in living organisms, which plays an important regulatory role in …

[HTML][HTML] Pharmacological Activities of Zingiber officinale Roscoe: Inhibition of HSA Protein Glycation, Structure Stability and Function Restoration

MWA Khan, S Sherwani, MHE Alshammari… - Pharmaceuticals, 2024 - mdpi.com
Background: Controlled non-enzymatic glycation reactions are common under normal
physiological conditions. However, during elevated blood glucose conditions, the glycation …

Cytochrome c as a distinct modulator of amyloid-beta amyloidogenesis in a peroxide-dependent manner

Z Du, E Nam, Y Lin, M Hong, T Molnár, I Kondo… - 2022 - chemrxiv.org
Cytochrome c (Cyt c) is an important, multifunctional protein for controlling cell fate.
Emerging evidence suggests a potential role of Cyt c in the amyloid pathology associated …