Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Recent advances in ophthalmic preparations: Ocular barriers, dosage forms and routes of administration

FA Maulvi, KH Shetty, DT Desai, DO Shah… - International journal of …, 2021 - Elsevier
The human eye is a complex organ with unique anatomy and physiology that restricts the
delivery of drugs to target ocular tissues/sites. Recent advances in the field of pharmacy …

Emerging potential of niosomes in ocular delivery

A Verma, A Tiwari, S Saraf, PK Panda… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Niosomes have recently grabbed attention as one of the best tools for various
site-specific drug delivery systems, including ophthalmic drug delivery. Surfactants …

Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo …

A Emad Eldeeb, S Salah, M Ghorab - Drug delivery, 2019 - Taylor & Francis
Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of
glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring …

TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells

H Hegazy, MM Amin, W Fayad, MY Zakaria - International Journal of …, 2022 - Elsevier
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …

Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …

S Ahmed, MM Amin, SM El-Korany, S Sayed - Drug Delivery, 2022 - Taylor & Francis
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …

Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity

S Ahmed, MM Farag, MA Sadek… - Journal of Liposome …, 2024 - Taylor & Francis
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …

'Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity': in-vitro and insilico studies

MY Zakaria, SM Abd El-Halim, BY Beshay, I Zaki… - Drug Delivery, 2023 - Taylor & Francis
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) predisposed to the
emergence of worldwide catastrophe that impels the evolution of safe and effective …

Ocular inserts of voriconazole-loaded proniosomal gels: formulation, evaluation and microbiological studies

GA El-Emam, GNS Girgis, MMA El-Sokkary… - International Journal …, 2020 - Taylor & Francis
Background Voriconazole (VRC) is a triazole broad spectrum antifungal drug, used in the
management of versatile fungal infections, particularly fungal keratitis. The obligatory use of …

Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …

MY Zakaria, WA Eraqi, SA Mohamed - International Journal of …, 2023 - Elsevier
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …