Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …
MH Do, E Lee, MJ Oh, Y Kim, HY Park - Nutrients, 2018 - mdpi.com
High fat diet-induced changes in gut microbiota have been linked to intestinal permeability and metabolic endotoxemia, which is related to metabolic disorders. However, the influence …
During aging, body adiposity increases with changes in the metabolism of lipids and their metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …
RA van der Heijden, F Sheedfar, MC Morrison… - Aging (Albany …, 2015 - ncbi.nlm.nih.gov
Metabolic inflammation in adipose tissue and the liver is frequently observed as a result of diet-induced obesity in human and rodent studies. Although the adipose tissue and the liver …
A Demers, S Samami, B Lauzier… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes the degradation of the low-density lipoprotein receptor thereby elevating plasma low-density lipoprotein …
MS Siersbæk, N Ditzel, EK Hejbøl, SM Præstholm… - Scientific reports, 2020 - nature.com
Abstract C57BL/6J-related mouse strains are widely used animal models for diet-induced obesity (DIO). Multiple vendors breed C57BL/6J-related substrains which may introduce …
AM Enciu, E Radu, ID Popescu… - BioMed research …, 2018 - Wiley Online Library
Metastasis requires cellular changes related to cell‐to‐cell and cell‐to‐matrix adhesion, immune surveillance, activation of growth and survival signalling pathways, and epigenetic …
Introduction There are inconsistent findings regarding the effect of lipid-lowering agents on nonalcoholic fatty liver disease (NAFLD). Proprotein Convertase Subtilisin/Kexin type 9 …
U Karunakaran, S Elumalai, JS Moon, KC Won - Cells, 2021 - mdpi.com
The cluster of differentiation 36 (CD36) is a scavenger receptor present on various types of cells and has multiple biological functions that may be important in inflammation and in the …