Type-2 diabetes mellitus is one of the most prevalent metabolic diseases in the world, and is
characterized by hyperglycemia (ie, high levels of glucose in the blood). Alpha-glucosidases …

Endoplasmic reticulum (ER)-resident α-glucosidases I and II sequentially trim the three
terminal glucose moieties on N-linked glycans attached to nascent glycoproteins. These …

Artemisia genus of Asteraceae family is a source of medicinal plants known worldwide and
used as ethnopharmacological remedies for the treatment of diabetes in Northern Asia …

Alpha-amylase is widely exploited as a drug target for preventing postprandial
hyperglycemia in diabetes and other metabolic diseases. Inhibition of this enzyme by plant …

In this work, a novel series of cyanoacetohydrazide linked to 1, 2, 3-triazoles (9a–n) were
designed and synthesized to be evaluated for their anti-α-glucosidase activity, focusing on …

A simple and efficient protocol was developed to synthesize a new library of thiazolidine-4-
one molecular hybrids (4a-n) via a one-pot multicomponent reaction involving 5-substituted …

Bioactive peptides are emerging as promising class of drugs that could serve as α‐
glucosidase inhibitors for the treatment of type 2 diabetes. This article identifies structural …

Two new manganese (II) complexes based on bisaroylhydrazone derivatives:[Mn II (L 1) 2
(NO 3) 2](1) and [Mn II (L 2) 2 (NO 3) 2](2) were synthesized via the reaction of manganese …

Abstract Treatment of type 2 diabetes is achieved through the inhibition of carbohydrate
hydrolyzing enzymes such as α-glucosidase and α-amylase. The present study was …

Diabetes is one of the pre-dominant metabolic disorders all over the world. It is the prime
reason of mortality and morbidity due to hyperglycemia which is link with numerus obstacles …