Importance of crosstalk between chronic lymphocytic leukemia cells and the stromal microenvironment: direct contact, soluble factors, and extracellular vesicles

N Dubois, E Crompot, N Meuleman, D Bron… - Frontiers in …, 2020 - frontiersin.org
Chronic lymphocytic leukemia (CLL) is caused by the accumulation of malignant B cells due
to a defect in apoptosis and the presence of small population of proliferating cells principally …

Tunneling nanotubes: The intercellular conduits contributing to cancer pathogenesis and its therapy

PK Melwani, BN Pandey - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …

Tunneling nanotubes: a new target for nanomedicine?

I Ottonelli, R Caraffi, G Tosi, MA Vandelli… - International Journal of …, 2022 - mdpi.com
Tunneling nanotubes (TNTs), discovered in 2004, are thin, long protrusions between cells
utilized for intercellular transfer and communication. These newly discovered structures …

NK cells and monocytes modulate primary HTLV-1 infection

R Moles, S Sarkis, V Galli, M Omsland, M Artesi… - PLoS …, 2022 - journals.plos.org
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …

Opportunities and challenges in tunneling nanotubes research: how far from clinical application?

X Han, X Wang - International journal of molecular sciences, 2021 - mdpi.com
Tunneling nanotubes (TNTs) are recognized long membrane nanotubes connecting
distance cells. In the last decade, growing evidence has shown that these subcellular …

Fluorescent artificial antigens revealed extended membrane networks utilized by live dendritic cells for antigen uptake

H Jing, B Saed, M Pálmai, H Gunasekara, PT Snee… - Nano Letters, 2022 - ACS Publications
Dendritic cells (DCs) can infiltrate tight junctions of the epithelium to collect remote antigens
during immune surveillance. While elongated membrane structures represent a plausible …

Specialized intercellular communications via tunnelling nanotubes in acute and chronic leukemia

A Allegra, M Di Gioacchino, G Cancemi, M Casciaro… - Cancers, 2022 - mdpi.com
Simple Summary Tunneling nanotubes (TNTs) are cytoplasmic channels which regulate the
contacts between cells and allow the transfer of several elements, including ions …

The mechanisms of mutual relationship between malignant hematologic cells and mesenchymal stem cells: Does it contradict the nursing role of mesenchymal stem …

A Goodarzi, M Valikhani, F Amiri, A Safari - Cell Communication and …, 2022 - Springer
Mesenchymal stem/stromal cells (MSCs) are known as the issue in biology because of some
unpredictable characteristics in the different microenvironments especially in their bone …

Transient viral activation in human T cell leukemia virus type 1-infected macaques treated with Pomalidomide

A Gutowska, K McKinnon, S Sarkis, MN Doster… - Frontiers in …, 2022 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) persists in the host despite a vigorous immune
response that includes cytotoxic T cells (CTL) and natural killer (NK) cells, suggesting the …

[HTML][HTML] Tunneling Nanotubes: The Transport Highway for Astrocyte-Neuron Communication in the Central Nervous System

C Zhou, M Huang, S Wang, S Chu, Z Zhang… - Brain Research …, 2024 - Elsevier
Tunneling nanotubes (TNTs) have emerged as pivotal structures for intercellular
communication, enabling the transfer of cellular components across distant cells. Their …