Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Salmonella species can infect a diverse range of birds, reptiles, and mammals, including
humans. The type III protein secretion system (T3SS) encoded by Salmonella pathogenicity …

Bile salts and bacteria have intricate relationships. The composition of the intestinal pool of
bile salts is shaped by bacterial metabolism. In turn, bile salts play a role in intestinal …

Bacterial transcriptional networks consist of hundreds of transcription factors and thousands
of promoters. However, the true complexity of transcription in a bacterial pathogen and the …

Commensal and pathogenic microorganisms must resist the deleterious actions of bile in
order to survive in the human gastrointestinal tract. Herein we review the current knowledge …

The ability of Salmonella to form complex surface-associated communities, called biofilms,
contributes to its resistance and persistence in both host and non-host environments and is …

Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …

Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …

Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

Despite major treatment and prevention efforts, millions of new typhoid infections occur
worldwide each year. For a subset of infected individuals, Salmonella enterica subsp …