Objective To determine the benefits and harms of medical cannabis and cannabinoids for
chronic pain. Design Systematic review and meta-analysis. Data sources MEDLINE …

Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …

Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational
and medicinal purposes. In many countries, cannabis‐based medicines have been …

Background Cannabis legalization has enabled increased consumption in older adults. Age-
related mental, physical, and physiological changes may lead to differences in effects of …

Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR
family. The biological functions are complex and diverse. PPARγ plays a significant role in …

Lipids, defined by low solubility in water and high solubility in nonpolar solvents, can be
classified into fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and sterols …

Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from
chemical compounds to light. Here, we exploit the remarkable sensing capacity of G-protein …

Background There is a paucity of high-quality data on patient outcomes and safety after
initiating treatment with cannabis-based medicinal products (CBMPs). The aim of this study …

Abstract Study Objectives We conducted a systematic review to explore the effectiveness of
medical cannabis for impaired sleep. Methods We searched MEDLINE, EMBASE …