Type three secretion system in Salmonella Typhimurium: the key to infection
AMP Dos Santos, RG Ferrari, CA Conte-Junior - Genes & genomics, 2020 - Springer
Abstract Background Type Three Secretion Systems (T3SS) are nanomachine complexes,
which display the ability to inject effector proteins directly into host cells. This skill allows for …
which display the ability to inject effector proteins directly into host cells. This skill allows for …
Host Genome-Wide Association Study of Infant Susceptibility to Shigella-Associated Diarrhea
Shigella is a leading cause of moderate-to-severe diarrhea globally and the causative agent
of shigellosis and bacillary dysentery. Associated with 80 to 165 million cases of diarrhea …
of shigellosis and bacillary dysentery. Associated with 80 to 165 million cases of diarrhea …
Vimentin regulates chemokine expression and NOD2 activation in brain endothelium during group B streptococcal infection
R Villarreal, HS Manzer… - Infection and …, 2021 - Am Soc Microbiol
Streptococcus agalactiae (group B Streptococcus, or GBS) is an opportunistic pathogen
capable of causing invasive disease in susceptible individuals, including the newborn …
capable of causing invasive disease in susceptible individuals, including the newborn …
Topological analysis of the type 3 secretion system translocon pore protein IpaC following its native delivery to the plasma membrane during infection
BC Russo, JK Duncan, MB Goldberg - MBio, 2019 - Am Soc Microbiol
Many Gram-negative bacterial pathogens require a type 3 secretion system (T3SS) to
deliver effector proteins into eukaryotic cells. Contact of the tip complex of the T3SS with a …
deliver effector proteins into eukaryotic cells. Contact of the tip complex of the T3SS with a …
Topology and contribution to the pore channel lining of plasma membrane-embedded Shigella flexneri type 3 secretion translocase IpaB
P Chen, BC Russo, JK Duncan-Lowey, N Bitar… - MBio, 2021 - Am Soc Microbiol
Shigella spp. are human bacterial pathogens that cause bacillary dysentery. Virulence
depends on a type 3 secretion system (T3SS), a highly conserved structure present in …
depends on a type 3 secretion system (T3SS), a highly conserved structure present in …
High-Throughput CRISPR Screens To Dissect Macrophage-Shigella Interactions
Shigellosis causes most diarrheal deaths worldwide, particularly affecting children. Shigella
invades and replicates in the epithelium of the large intestine, eliciting inflammation and …
invades and replicates in the epithelium of the large intestine, eliciting inflammation and …
Measurement of Yersinia Translocon Pore Formation in Erythrocytes
TRD Costa, MK Francis, SI Farag, T Edgren… - … Yersinia: Methods and …, 2019 - Springer
Many Gram-negative pathogens produce a type III secretion system capable of intoxicating
eukaryotic cells with immune-modulating effector proteins. Fundamental to this injection …
eukaryotic cells with immune-modulating effector proteins. Fundamental to this injection …
Host-pathogen interactions: What the EHEC are we learning from host genome-wide Screens?
Several genome-wide screens have been conducted to identify host cell factors involved in
the pathogenesis of bacterial pathogens whose virulence is dependent on type III secretion …
the pathogenesis of bacterial pathogens whose virulence is dependent on type III secretion …