Innate inspiration: antifungal peptides and other immunotherapeutics from the host immune response
DK Mercer, DA O'Neil - Frontiers in Immunology, 2020 - frontiersin.org
The purpose of this review is to describe antifungal therapeutic candidates in preclinical and
clinical development derived from, or directly influenced by, the immune system, with a …
clinical development derived from, or directly influenced by, the immune system, with a …
Combatting fungal infections: advances in antifungal polymeric nanomaterials
Fungal pathogens cause over 6.5 million life-threatening systemic infections annually, with
mortality rates ranging from 20 to 95%, even with medical intervention. The World Health …
mortality rates ranging from 20 to 95%, even with medical intervention. The World Health …
Hyperpolarisation of mitochondrial membranes is a critical component of the antifungal mechanism of the plant defensin, Ppdef1
Plant defensins are a large family of small cationic proteins with diverse functions and
mechanisms of action, most of which assert antifungal activity against a broad spectrum of …
mechanisms of action, most of which assert antifungal activity against a broad spectrum of …