The epithelium represents the first and most extensive line of defence against pathogens,
toxins and pollutant agents in humans. In general, pathogens have developed strategies to …

Entamoeba histolytica, the causative agent of human amoebiasis, exhibits a continuous
membrane remodelling to exert its virulence properties. During this dynamic process, the …

The endosomal sorting complex required for transport (ESCRT) orchestrates cell membrane-
remodeling mechanisms in eukaryotes, including endocytosis. However, ESCRT functions …

In humans and Drosophila melanogaster, the functional convergence of the endosomal
sorting complex required for transport (ESCRT) machinery that is in charge of selecting …

Dental plaque is closely related to the occurrence of dental caries, of which the main
causative bacterium is Streptococcus mutans (S. mutans). In this study, to create potent …

The retromer is a cellular structure that recruits and recycles proteins inside the cell. In
mammalian and yeast, the retromer components have been widely studied, but very little in …

During intestinal invasion, Entamoeba histolytica opens tight junctions (TJs) reflected by
transepithelial electrical resistance (TEER) dropping. To explore the molecular mechanisms …

The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0,
ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular …

The EhVps23 protein, an orthologue of the yeast Vps23 and the mammalian TSG101
proteins, is the single member of the ESCRT-I complex of Entamoeba histolytica identified …

Membrane fission triggered by the endosomal sorting complex required for transport
(ESCRT) is an important process observed in several pathogenic and non-pathogenic …