A spray drying technique was developed to prepare injectable and biodegradable poly
(lactic-co-glycolic acid)(PLGA) microspheres encapsulating a model luteinizing hormone …

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a
number of challenging conditions, allowing researchers to cross barriers that have …

Abstract Efavirenz (EFV), a first-line anti-HIV drug largely used as part of antiretroviral
therapies, is practically insoluble in water and belongs to BCS class II (low solubility/high …

Benznidazole (BNZ) is the drug of choice for the treatment of Chagas disease in many
countries. However, its low water solubility produces low and/or variable oral bioavailability …

This work aimed to design low-melting pressure sensitive adhesives and to demonstrate the
feasibility of the preparation of (trans) dermal patches by hot-melt ram extrusion printing …

Background: Spray drying has been used as a means to encapsulate therapeutics in
polymeric matrices to improve stability and alter pharmacokinetics. This research aims to …

Intranasal delivery is an alternative method to target therapeutics to the central nervous
system. In the present study, chitosan glutamate (CG)-based mucoadhesive microspheres …

This study aimed to develop a multiparticulate system based on sodium alginate/gellan gum
polymers for morin controlled release using standardized spray-dryer parameters. A 2 4 …

Acanthamoeba spp. are the causative agents of granulomatous amoebic encephalitis (GAE)
and amoebic keratitis. Recent studies performed by Rassu et al. showed that, compared with …

Acrylic enteric microparticles for oral drug delivery were prepared by an oil-in-oil emulsion
solvent evaporation process. The novel use of sorbitan sesquioleate as a surfactant …