Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that
affect the structure, function, or production of red blood cells (RBCs). These disorders can …

Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes that also control
cytokine-induced peroxide levels which mediate signal transduction in mammalian cells …

Cryoelectron microscopy of biological molecules is among the hottest growth areas in
biophysics and structural biology at present, and Frank is arguably the most distinguished …

Present knowledge on peroxiredoxins is reviewed with special emphasis on catalytic
principles, specificities and biological function. Peroxiredoxins are low efficiency …

Organisms living under aerobic conditions have developed various anti-oxidative
mechanisms to protect them from damage by reactive oxygen species (ROS). A novel family …

Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein
interactions. Understanding the role of the multiple structural and post-translational …

In this review we cover the technical background to negative staining of biomolecules and
viruses, and then expand upon the different possibilities and limitations. Topics range from …

Peroxiredoxin 2 (Prx2) is an antioxidant enzyme that uses cysteine residues to decompose
peroxides. Prx2 is the third most abundant protein in erythrocytes, and competes effectively …

Fifteen years ago, in 2001, the concept of “Reactive Sulfur Species” or RSS was advocated
as a working hypothesis. Since then various organic as well as inorganic RSS have …

In this personal, historic account of macromolecular transmission electron microscopy
(TEM), published data from the 1940s through to recent times is surveyed, within the context …