Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …

Neurotransmitters and neuromodulators have a wide range of key roles throughout the
nervous system. However, their dynamics in both health and disease have been challenging …

The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

A fundamental challenge in fluorescence microscopy is the photon shot noise arising from
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …

Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …

Intensiometric genetically encoded biosensors, based on allosteric modulation of the
fluorescence of a single fluorescent protein, are powerful tools for enabling imaging of …

Gamma-aminobutyric acid (GABA) is a ubiquitous four-carbon, non-protein amino acid.
GABA has been widely studied in animal central nervous systems, where it acts as an …

The non-protein amino acid γ-aminobutyric acid (GABA) has been proposed to be an
ancient messenger for cellular communication conserved across biological kingdoms. GABA …

Interest in deciphering the fundamental mechanisms and processes of the human mind
represents a central driving force in modern neuroscience research. Activities in support of …