Challenges in exosome isolation and analysis in health and disease

N Ludwig, TL Whiteside, TE Reichert - International journal of molecular …, 2019 - mdpi.com
A growing body of evidence emphasizes the important role exosomes in different
physiological and pathological conditions. Exosomes, virus-size extracellular vesicles (EVs) …

Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers

P Simeone, G Bologna, P Lanuti… - International journal of …, 2020 - mdpi.com
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

Presence of Tat and transactivation response element in spinal fluid despite antiretroviral therapy

LJ Henderson, TP Johnson, BR Smith, LB Reoma… - Aids, 2019 - journals.lww.com
Objective: The aim of this study was to measure the protein concentration and biological
activity of HIV-1 Tat in cerebrospinal fluid (CSF) of individuals on suppressive antiretroviral …

Imaging of surface microdomains on individual extracellular vesicles in 3‐D

RP McNamara, Y Zhou, AB Eason… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are secreted from all cell types and are intimately involved in
tissue homeostasis. They are being explored as vaccine and gene therapy platforms, as well …

MicroRNAs and exosomes: key players in HIV pathogenesis

J Sadri Nahand, F Bokharaei‐Salim… - HIV …, 2020 - Wiley Online Library
Objectives HIV infection is well known to cause impairment of the human immune system,
and until recently was a leading cause of death. It has been shown that T lymphocytes are …

Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

RP McNamara, CP Caro-Vegas… - Journal of …, 2018 - Taylor & Francis
Isolation of extracellular vesicles (EVs) from cell culture supernatant or plasma can be
accomplished in a variety of ways. Common measures to quantify relative success are …

HIV-1 latency and viral reservoirs: existing reversal approaches and potential technologies, targets, and pathways involved in HIV latency studies

S Khanal, M Schank, M El Gazzar, JP Moorman… - Cells, 2021 - mdpi.com
Eradication of latent human immunodeficiency virus (HIV) infection is a global health
challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick …

Intrinsic factors behind long‐COVID: I. Prevalence of the extracellular vesicles

YA El‐Maradny, A Rubio‐Casillas… - Journal of Cellular …, 2023 - Wiley Online Library
It can be argued that the severity of COVID‐19 has decreased in many countries. This could
be a result of the broad coverage of the population by vaccination campaigns, which often …

[HTML][HTML] Seminal exosomes–an important biological marker for various disorders and syndrome in human reproduction

AS Vickram, PS Srikumar, S Srinivasan… - Saudi journal of …, 2021 - Elsevier
Background Exosomes are nano-sized membrane vesicles, secreted by different types of
cells into the body's biological fluids. They are found in abundance in semen as compared to …

HTLV-1 extracellular vesicles promote cell-to-cell contact

DO Pinto, C DeMarino, ML Pleet, M Cowen… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia virus-1 (HTLV-1) is a neglected and incurable retrovirus estimated to
infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection …