Recent advances in protein analysis by capillary and microchip electrophoresis

M Dawod, NE Arvin, RT Kennedy - Analyst, 2017 - pubs.rsc.org
This review article describes the significant recent advances in the analysis of proteins by
capillary and microchip electrophoresis during the period from mid-2014 to early 2017. This …

Recent applications of microchip electrophoresis to biomedical analysis

N Nuchtavorn, W Suntornsuk, SM Lunte… - … of Pharmaceutical and …, 2015 - Elsevier
Many separation methods have been developed for biomedical analysis, including
chromatographic (eg high performance liquid chromatography (HPLC) and gas …

Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size

NE Pryor, MA Moss, CN Hestekin - International Journal of Molecular …, 2012 - mdpi.com
The aggregation of proteins into insoluble amyloid fibrils coincides with the onset of
numerous diseases. An array of techniques is available to study the different stages of the …

On-chip magneto-immunoassay for Alzheimer's biomarker electrochemical detection by using quantum dots as labels

M Medina-Sánchez, S Miserere… - Biosensors and …, 2014 - Elsevier
Electrochemical detection of cadmium-selenide/zinc-sulfide (CdSe@ ZnS) quantum dots
(QDs) as labeling carriers in an assay for apolipoprotein E (ApoE) detection has been …

[HTML][HTML] Nanomaterials in microchip electrophoresis–A review

M Jozanović, I Pukleš, N Sakač, E Carrilho… - TrAC Trends in …, 2023 - Elsevier
Microchip electrophoresis is the most promising method for developing an integrated lab-on-
a-chip device for preconcentration, separation, and detection of various compounds in a …

Overview on microfluidics devices for monitoring brain disorder biomarkers

C Nix, M Ghassemi, J Crommen, M Fillet - TrAC Trends in Analytical …, 2022 - Elsevier
Neurological disorders are one of the leading causes of disability and death worldwide. The
complexity of the human brain and therefore the significant structural gap between animal …

Microfluidics as a novel tool for biological and toxicological assays in drug discovery processes: Focus on microchip electrophoresis

G Caruso, N Musso, M Grasso, A Costantino… - Micromachines, 2020 - mdpi.com
The last decades of biological, toxicological, and pharmacological research have deeply
changed the way researchers select the most appropriate 'pre-clinical model'. The absence …

Applications of microfluidics and microchip electrophoresis for potential clinical biomarker analysis

JV Pagaduan, V Sahore, AT Woolley - Analytical and bioanalytical …, 2015 - Springer
This article reviews advances over the last five years in microfluidics and microchip-
electrophoresis techniques for detection of clinical biomarkers. The variety of advantages of …

Blood brain barrier-on-a-chip to model neurological diseases

S Reshma, KB Megha, S Amir, S Rukhiya… - Journal of Drug Delivery …, 2023 - Elsevier
The blood-brain barrier (BBB) is a vital and unique multi-dimensional selective barrier that
helps maintain brain homeostasis. BBB is a complex and dynamic structure responsible for …

Single-step immunoassays and microfluidic droplet operation: Towards a versatile approach for detection of amyloid-β peptide-based biomarkers of Alzheimer's …

TD Mai, D Ferraro, N Aboud, R Renault, M Serra… - Sensors and Actuators B …, 2018 - Elsevier
In this study, single-step magnetic-beads based immunoassays was developed and for the
first time adapted to microfluidic droplet operation for sequential determination of well …