Intrinsically disordered proteins (IDPs) constitute a broad set of proteins with few uniting and
many diverging properties. IDPs—and intrinsically disordered regions (IDRs) interspersed …

Retinoic acid (RA) signaling pathways regulate fundamental biological processes, such as
cell proliferation, development, differentiation, and apoptosis. Retinoid receptors (RARs and …

Coarse-grained molecular dynamics simulations are a useful tool to determine
conformational ensembles of proteins. Here, we show that the coarse-grained force field …

Many disordered proteins conserve essential functions in the face of extensive sequence
variation, making it challenging to identify the mechanisms responsible for functional …

The formation and viscoelastic properties of condensates of intrinsically disordered proteins
(IDPs) is dictated by amino acid sequence and solution conditions. Because of the …

The three subtypes (α, β, and γ) of the retinoic acid receptor (RAR) are ligand-dependent
transcription factors that mediate retinoic acid signaling by forming heterodimers with the …

Many proteins contain more than one folded domain, and such modular multi‐domain
proteins help expand the functional repertoire of proteins. Because of their larger size and …

Vitamin A (retinol) is an essential micronutrient with a crucial role in the immune system of
non-ruminant animals, such as swine and poultry. It includes three chemical compounds …

The molecular chaperone Hsp90 supports the functional activity of specific substrate
proteins (clients). For client processing, the Hsp90 dimer undergoes a series of ATP‐driven …

In order to discover the active anti-tumor ingredients during the flavonoids separation
process of Ougan (Citrus reticulata cv. Suavissima), gastric cancer cell lines including AGS …