The hippocampus provided the gateway into much of what we have learned about stress
and brain structural and functional plasticity, and this initial focus has expanded to other …

Increasing evidence suggests estrogen and estrogen signaling pathway disturbances
across psychiatric disorders. Estrogens are not only crucial in sexual maturation and …

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic
branching, myelination and other important mechanisms of neural plasticity. Here we review …

▪ Abstract The hippocampus is a target of stress hormones, and it is an especially plastic and
vulnerable region of the brain. It also responds to gonadal, thyroid, and adrenal hormones …

Neurodegenerative disorders are characterized by extensive neuron death that leads to
functional decline, but the neurobiological correlates of functional decline in normal aging …

Estrogen Actions in the Central Nervous System* | Endocrine Reviews | Oxford Academic
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Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …

Besides affecting the hypothalamus and other brain areas related to reproduction, ovarian
steroids have widespread effects throughout the brain, on serotonin pathways …

Besides their well-established actions on reproductive functions, estrogens exert a variety of
actions on many regions of the nervous system that influence higher cognitive function, pain …

Previous studies have shown that estradiol induces new dendritic spines and synapses on
hippocampal CA1 pyramidal cells. We have assessed the consequences of estradiol …