The “Gum–Gut” axis in inflammatory bowel diseases: a hypothesis-driven review of associations and advances

KM Byrd, AS Gulati - Frontiers in immunology, 2021 - frontiersin.org
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper
airways and gastrointestinal tract; however, its connection to the rest of the body has been …

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

CGK Ziegler, VN Miao, AH Owings, AW Navia, Y Tang… - Cell, 2021 - cell.com
SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals
present with isolated upper respiratory symptoms, suggesting potential to constrain viral …

[HTML][HTML] Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity

DW Williams, T Greenwell-Wild, L Brenchley, N Dutzan… - Cell, 2021 - cell.com
The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to
antigens and commensals, and a tissue susceptible to one of the most prevalent human …

COVID-19 and dentistry in 72 questions: An overview of the literature

S Derruau, J Bouchet, A Nassif, A Baudet… - Journal of Clinical …, 2021 - mdpi.com
The outbreak of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has significantly affected the dental …

[PDF][PDF] The COVID-19 pathway: a proposed oral-vascular-pulmonary route of SARS-CoV-2 infection and the importance of oral healthcare measures

G Lloyd-Jones, S Molayem, CC Pontes… - J Oral Med Dent …, 2021 - drkearney.co.za
Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infections in late 2019, the world has faced a major healthcare challenge. There remains …

Coronavirus 2019 infectious disease epidemic: where we are, what can be done and hope for

M Carbone, J Lednicky, SY Xiao, M Venditti… - Journal of Thoracic …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads mainly by means
of aerosols (microdroplets) in enclosed environments, especially those in which temperature …

Dental biofilm of symptomatic COVID‐19 patients harbours SARS‐CoV‐2

SC Gomes, S Fachin, JG da Fonseca… - Journal of clinical …, 2021 - Wiley Online Library
Abstract Aims SARS‐CoV‐2 RNA has been recovered from different sites in the human
body, including the mouth. The present study aimed to investigate the presence of SARS …

The human salivary proteome wiki: a community-driven research platform

WW Lau, M Hardt, YH Zhang… - Journal of Dental …, 2021 - journals.sagepub.com
Saliva has become an attractive body fluid for on-site, remote, and real-time monitoring of
oral and systemic health. At the same time, the scientific community needs a saliva-centered …

[HTML][HTML] Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

JP Shannon, SM Vrba, GV Reynoso, E Wynne-Jones… - Immunity, 2021 - cell.com
The oropharyngeal mucosa serves as a perpetual pathogen entry point and a critical site for
viral replication and spread. Here, we demonstrate that type 1 innate lymphoid cells (ILC1s) …

POU2F3 beyond thymic carcinomas: expression across the spectrum of thymomas hints to medullary differentiation in type A thymoma

Y Yamada, A Sugimoto, M Hoki, A Yoshizawa… - Virchows Archiv, 2022 - Springer
The thymic medulla comprises various cell types, including tuft cells that are involved in
innate immunity. We recently reported that in Western cohorts of patients, most thymic …