Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

Generating force and movement is essential for the functions of cells and organisms. A
variety of molecular motors that can move on tracks within cells have evolved to serve this …

Pumps and motors are essential components of the world as we know it. From the complex
proteins that sustain our cells, to the mechanical marvels that power industries, much we …

Molecular machines are essential dynamic components for fuel production, cargo delivery,
information storage and processing in living systems. Scientists have demonstrated that they …

In the cytosol, actin polymers, intermediate filaments and microtubules can anchor to cell
surface adhesions and interlink to form intricate networks. This cytoskeleton is anchored to …

Through complementary application of SNP genotyping, whole-genome sequencing and
imputation in 38,384 Icelanders, we have discovered a previously unidentified sick sinus …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Myosins are a large family of actin-based cytoskeletal motors that use energy derived from
ATP hydrolysis to generate movement and force. Myosins of classes II, V and VI have …

Processivity, the ability of single molecules to move continuously along a track, is a
fundamental requirement of cargo-transporting molecular motors. Here, we investigate how …

Myosins are key components of the eukaryotic cytoskeleton, providing motility for a broad
diversity of cargoes. Therefore, understanding the origin and evolutionary history of myosin …