Vasoplegic syndrome following cardiothoracic surgery—review of pathophysiology and update of treatment options

LW Busse, N Barker, C Petersen - Critical Care, 2020 - Springer
Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is
characterized as a high-output shock state with poor systemic vascular resistance. The …

What's new in cardiopulmonary bypass

EA Hessel II - Journal of cardiothoracic and vascular anesthesia, 2019 - Elsevier
This is a narrative review of recent articles (mainly published in 2017 and 2018) related to
the conduct of cardiopulmonary bypass (CPB) that should be of interest to the cardiac …

Hydroxocobalamin for the treatment of vasoplegia: a review of current literature and considerations for use

AD Shapeton, F Mahmood… - Journal of Cardiothoracic …, 2019 - jcvaonline.com
VASOPLEGIA is a term used to describe hypotension in the setting of high pressor
requirements and normal or increased cardiac output. A commonly used numerical …

Vasoplegic syndrome: an update on perioperative considerations

H Liu, L Yu, L Yang, MS Green - Journal of clinical anesthesia, 2017 - Elsevier
Vasoplegic syndrome (VS) is increasingly recognized as an important clinical entity in
perioperative medicine. VS is characterized by significant arterial hypotension, normal or …

Vasoplegia after cardiopulmonary bypass: A narrative review of pathophysiology and emerging targeted therapies

TJ Barnes, MA Hockstein… - SAGE open medicine, 2020 - journals.sagepub.com
Cardiovascular disease remains the leading cause of death in the United States, and
cardiopulmonary bypass is a cornerstone in the surgical management of many related …

Hydroxocobalamin for the treatment of cardiac surgery-associated vasoplegia: a case series

PR Shah, PS Reynolds, N Pal, D Tang… - Canadian Journal …, 2018 - search.proquest.com
Purpose Vasoplegia is a clinical syndrome marked by severe arteriolar vasodilatation,
hypotension, and low systemic vascular resistance refractory to multiple vasopressor …

The use of intravenous hydroxocobalamin as a rescue in methylene blue-resistant vasoplegic syndrome in cardiac surgery

Y Cai, A Mack, BL Ladlie, AK Martin - Annals of cardiac …, 2017 - journals.lww.com
Vasoplegic syndrome is a well-recognized complication during cardiopulmonary bypass
(CPB) and is associated with increased morbidity and mortality, especially when refractory to …

Methylene blue monotherapy compared with combination therapy with hydroxocobalamin for the treatment of refractory vasoplegic syndrome: aRetrospective cohort …

JT Feih, JRG Rinka, MT Zundel - Journal of Cardiothoracic and Vascular …, 2019 - Elsevier
Objective To compare the efficacy of methylene blue with combination therapy with
hydroxocobalamin in patients experiencing vasoplegic syndrome after cardiac surgery …

Effects of a single bolus of hydroxocobalamin on hemodynamics in vasodilatory shock

LA Ritter, M Maldarelli, MT McCurdy, DP Yamane… - Journal of critical …, 2022 - Elsevier
Purpose Hydroxocobalamin has been observed to cause transient hypertension in healthy
subjects, but rigorous studies examining its efficacy are lacking. Materials and methods …

Vitamin B12 for the treatment of vasoplegia in cardiac surgery and liver transplantation: a narrative review of cases and potential biochemical mechanisms

C Fritz-Gerald, LJ Murray, C Giordano… - Canadian Journal of …, 2019 - search.proquest.com
Purpose Hydroxocobalamin, or vitamin B12 (V-B12), is frequently used to treat smoke
inhalation and cyanide poisoning. Recent reports have also described its use to treat …