Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Helicobacter pylori pathogenesis and disease outcomes are mediated by a complex
interplay between bacterial virulence factors, host, and environmental factors. After H. pylori …

Chimeric antigen receptor T cells (CAR T cells) are effective against haematologic
malignancies. However, in solid tumours, their potency is hampered by local …

Gastric cancer is a challenging public health concern worldwide and remains a leading
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …

Helicobacter pylori neutrophil-activating protein (HP-NAP), a major virulence factor of H.
pylori, plays a role in bacterial protection and host inflammation. HP-NAP activates a variety …

Chimeric antigen receptor T cells (CAR-T) therapy has shown great potential in tumor
treatment. However, many factors impair the efficacy of CAR-T therapy, such as antigenic …

The Gram-negative bacterium Helicobacter pylori colonizes ca 50% of human stomachs
worldwide and is the major risk factor for gastric adenocarcinoma. Its high genetic variability …

The miniferritin HP-NAP of Helicobacter pylori was originally described as a neutrophil-
activating protein because of the capacity to activate neutrophils to generate oxygen radicals …

Background The progression to gastric cancer has been linked to chronic infection with
Helicobacter pylori (H. pylori). Immune checkpoint inhibitors (programmed cell death-1, PD …

Many studies point to an association between Helicobacter pylori (H. pylori) infection and
inflammatory bowel diseases (IBD). Although controversial, this association indicates that …