Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment

S Qi, N Duan, IM Khan, X Dong, Y Zhang, S Wu… - Biotechnology …, 2022 - Elsevier
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Non-immobilized GO-SELEX of aptamers for label-free detection of thiamethoxam in vegetables

Q Kong, F Yue, M Liu, J Huang, F Yang, J Liu, J Li… - Analytica Chimica …, 2022 - Elsevier
Due to the massive use of thiamethoxam (TMX) pesticide and the accumulated potential
hazards exposure, the detection of TMX is of great significance to food and ecological safety …

A bifunctional core–shell gold@ Prussian blue nanozyme enabling dual-readout microfluidic immunoassay of food allergic protein

X Zhang, Y Shi, D Wu, L Fan, J Liu, Y Wu, G Li - Food chemistry, 2024 - Elsevier
Food allergy has posed a great threat for public health due to its rising prevalence
worldwide, and thus sensitive and reliable food allergen monitoring methods is of great …

based microfluidic device for selective detection of peanut allergen Ara h1 applying black phosphorus-Au nanocomposites for signal amplification

M Pan, X Han, S Chen, J Yang, Y Wang, H Li, S Wang - Talanta, 2024 - Elsevier
This paper developed a portable microfluidic paper-based analysis device (μ-PAD)
combined with the electrochemical technique for efficient and sensitive detection of peanut …

Recent developments in application of nucleic acid aptamer in food safety

JJ Kalita, P Sharma, U Bora - Food Control, 2023 - Elsevier
Food, a basic necessity of life, is often contaminated with harmful agents like pathogenic
microorganisms, biotoxins, allergens, antibiotic residues, pesticides, heavy metals etc …

Selection of broad-spectrum aptamer and its application in fabrication of aptasensor for detection of aminoglycoside antibiotics residues in milk

F Yue, H Li, Q Kong, J Liu, G Wang, F Li, Q Yang… - Sensors and Actuators B …, 2022 - Elsevier
The multi-residues of aminoglycoside antibiotics (AAs) have been reported present in a food
product. Taking the broad-spectrum aptamer as recognition element of sensors for …

High-stable perovskite nanocrystal fluorescent probe-based aptasensor for ultrasensitive detection of peanut allergen Ara h1

S Qi, A Sun, X Dong, Y Sun, M Qin, N Ding… - Sensors and Actuators B …, 2023 - Elsevier
Food allergy is a serious immune allergy reaction, that has attracted public attention all over
the world due to the increasing incidence. Ara h1, the most abundant allergenic protein in …

A novel ratiometric aptasensor based on dual-emission fluorescent signals and the conformation of G-quadruplex for OTA detection

H Guo, P Ma, K Li, S Zhang, Y Zhang, H Guo… - Sensors and Actuators B …, 2022 - Elsevier
Ochratoxin A (OTA) is known as an important mycotoxin that is widely distributed in food
products. The increasing requirement for sensitive and convenient OTA detection has …

Structure-guided engineering of aptamers to enhanced structural stability and application performance in alleviating β-lactoglobulin allergenicity

S Qi, X Dong, S Niazi, M Lu, N Duan, Z Wang - Chemical Engineering …, 2023 - Elsevier
Aptamers are synthetic single-strand oligonucleotide-based ligands with great application
potential due to their intriguing properties of specific and high affinity target binding and …