Generating and using transcriptomically based retinal cell atlases
It has been known for over a century that the basic organization of the retina is conserved
across vertebrates. It has been equally clear that retinal cells can be classified into …
across vertebrates. It has been equally clear that retinal cells can be classified into …
[HTML][HTML] Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification
Precise temporal control of gene expression in neuronal progenitors is necessary for correct
regulation of neurogenesis and cell fate specification. However, the cellular heterogeneity of …
regulation of neurogenesis and cell fate specification. However, the cellular heterogeneity of …
[HTML][HTML] A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq
Recent advances in high throughput single-cell RNA sequencing (scRNA-seq) technology
have enabled the simultaneous transcriptomic profiling of thousands of individual cells in a …
have enabled the simultaneous transcriptomic profiling of thousands of individual cells in a …
Molecular signatures of retinal ganglion cells revealed through single cell profiling
Retinal ganglion cells can be classified into more than 40 distinct subtypes, whether by
functional classification or transcriptomics. The examination of these subtypes in relation to …
functional classification or transcriptomics. The examination of these subtypes in relation to …
Molecular basis of retinal remodeling in a zebrafish model of retinitis pigmentosa
A hallmark of inherited retinal degenerative diseases such as retinitis pigmentosa (RP) is
progressive structural and functional remodeling of the remaining retinal cells as …
progressive structural and functional remodeling of the remaining retinal cells as …
Chromatin accessibility and transcriptional differences in human stem cell-derived early-stage retinal organoids
MK Jones, D Agarwal, KW Mazo, M Chopra, SL Jurlina… - Cells, 2022 - mdpi.com
Retinogenesis involves the specification of retinal cell types during early vertebrate
development. While model organisms have been critical for determining the role of dynamic …
development. While model organisms have been critical for determining the role of dynamic …
Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of …
YJ Chan, G Hsiao, WN Wan, TM Yang, CH Tsai… - Fluids and Barriers of …, 2023 - Springer
Blue light is part of the natural light spectrum that emits high energy. Currently, people are
frequently exposed to blue light from 3C devices, resulting in a growing incidence of …
frequently exposed to blue light from 3C devices, resulting in a growing incidence of …
Latent epigenetic programs in Müller glia contribute to stress and disease response in the retina
JL Norrie, MS Lupo, DR Little, A Shirinifard, A Mishra… - Developmental Cell, 2025 - cell.com
Previous studies have demonstrated the dynamic changes in chromatin structure during
retinal development correlate with changes in gene expression. However, those studies lack …
retinal development correlate with changes in gene expression. However, those studies lack …
Reviewing guppy color vision: integrating the molecular and physiological variation in visual tuning of a classic system for sensory drive
Sensory drive predicts coevolution of mate choice signals with the sensory systems
detecting those signals. Guppies are a classic model for sensory drive as mate preferences …
detecting those signals. Guppies are a classic model for sensory drive as mate preferences …
Comprehensive analysis of retinal development at single cell resolution identifies NFI factors as essential for mitotic exit and specification of late-born cells
Precise temporal control of gene expression in neuronal progenitors is necessary for correct
regulation of neurogenesis and cell fate specification. However, the extensive cellular …
regulation of neurogenesis and cell fate specification. However, the extensive cellular …