Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine

J Nijs, SZ George, DJ Clauw… - The Lancet …, 2021 - thelancet.com
Chronic pain is a leading cause of disability globally and associated with enormous health-
care costs. The discrepancy between the extent of tissue damage and the magnitude of …

Central sensitization in cancer survivors and its clinical implications: state of the art

T Nishigami, M Manfuku, A Lahousse - Journal of Clinical Medicine, 2023 - mdpi.com
Although the prevalence of cancer pain is 47% after treatment, cancer pain is often
underestimated, and many patients are undertreated. The complexity of cancer pain …

Effects of transcranial direct current stimulation on pain and physical function in patients with knee osteoarthritis: a systematic review and meta-analysis

Y Wu, Y Luo, J Yang, Y Wu, Q Zhu, Y Li, H Hu… - BMC Musculoskeletal …, 2024 - Springer
Abstract Background Keen Osteoarthritis (KOA) is a common chronic disabling disease
characterized by joint pain and dysfunction, which seriously affects patients' quality of life …

The effect of a psychologically informed video series to treat adolescents with patellofemoral pain: a randomized controlled trial

M Selhorst, J Hoehn, L Schmitt, J Benedict… - journal of orthopaedic & …, 2023 - jospt.org
OBJECTIVE: To test whether a series of brief, psychologically informed educational videos
added to physical therapy improved function among adolescents with patellofemoral pain …

Does central nervous system dysfunction underlie patellofemoral pain in young females? Examining brain functional connectivity in association with patient‐reported …

JA Diekfuss, DR Grooms, KS Nissen… - Journal of …, 2022 - Wiley Online Library
Patellofemoral pain (PFP) is defined as retro‐or peri‐patellar knee pain without a clear
structural abnormality. Unfortunately, many current treatment approaches fail to provide long …

Brain activity during experimental knee pain and its relationship with kinesiophobia in patients with patellofemoral pain: a preliminary functional magnetic resonance …

KDB Foss, AB Slutsky-Ganesh… - Journal of Sport …, 2022 - journals.humankinetics.com
Context: The etiology of patellofemoral pain has remained elusive, potentially due to an
incomplete understanding of how pain, motor control, and kinesiophobia disrupt central …

Hand-held dynamometer to measure pressure pain thresholds: a double-blinded reliability and validity study

DJ Jayaseelan, KR Cole, CA Courtney - Musculoskeletal Science and …, 2021 - Elsevier
Background Pain is the most common complaint reported in the musculoskeletal setting.
Quantitative sensory testing (QST) assists with pain mechanism identification, although QST …

Body fat and skeletal muscle mass, but not body mass index, are associated with pressure hyperalgesia in young adults with patellofemoral pain

AS Ferreira, S Lack, B Taborda, MF Pazzinatto… - Brazilian Journal of …, 2022 - Elsevier
Background Young adults with patellofemoral pain (PFP) have a high prevalence of being
overweight or obese, which is associated with impaired lower limb function and muscle …

Effectiveness of local exercise therapy versus spinal manual therapy in patients with patellofemoral pain syndrome: medium term follow-up results of a randomized …

A Scafoglieri, J Van den Broeck, S Willems… - BMC musculoskeletal …, 2021 - Springer
Background Increasing evidence has shown benefits of spinal manipulations in patients with
patellofemoral pain syndrome (PFPS). There is scarcity regarding medium term effects of …

Efficacy of home-based transcranial direct current stimulation on experimental pain sensitivity in older adults with knee osteoarthritis: a randomized, sham-controlled …

G Martorella, K Mathis, H Miao, D Wang, L Park… - Journal of clinical …, 2022 - mdpi.com
Although transcranial direct current stimulation (tDCS) is encouraging regarding clinical pain
intensity for individuals with knee osteoarthritis, very few studies have explored its impact on …