Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …

Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …

Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated
molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs), and …

Cerebral malaria (CM) is one of the leading causes of death due to malaria. It is
characterised by coma, presence of asexual parasites in blood smear, and absence of any …

Pathogens can release extracellular vesicles (EVs) for cell–cell communication and host
modulation. EVs from Plasmodium falciparum, the deadliest malaria parasite species, can …

Malaria is a major global health problem. Despite decades of research, there is still no
effective vaccine to prevent disease in the majority of people living in malaria‐endemic …

Malaria remains a serious threat to global health. Sustained malaria control and, eventually,
eradication will only be achieved with a broadly effective malaria vaccine. Yet a fundamental …

Immunity to Plasmodium falciparum malaria is slow to develop, and it is often asserted that
malaria suppresses host immunity, although this is poorly understood and the molecular …

Background Factors driving inter-individual differences in immune responses upon different
types of prenatal malaria exposure (PME) and subsequent risk of malaria in infancy remain …

The immune system of vertebrates includes innate immunity and adaptive immunity, and the
network between them enables the host to fight against invasions of various pathogens …