The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

Spinal cord injury is linked to the interruption of neural pathways, which results in
irreversible neural dysfunction. Neural repair and neuroregeneration are critical goals and …

The hippocampal dentate gyrus is often viewed as a segregator of upstream information.
Physiological support for such function has been hampered by a lack of well-defined …

Episodic memory formation and recall are complementary processes that rely on opposing
neuronal computations in the hippocampus. How this conflict is resolved in hippocampal …

Post-tetanic potentiation (PTP) is an attractive candidate mechanism for hippocampus-
dependent short-term memory. Although PTP has a uniquely large magnitude at …

Mice display signs of fear when neurons that express cFos during fear conditioning are
artificially reactivated. This finding gave rise to the notion that cFos marks neurons that …

Anatomical observations, theoretical work and lesion experiments have led to the idea that
an important function of the dentate gyrus of the mammalian hippocampus is pattern …

During immature stages, adult-born neurons pass through critical periods for survival and
plasticity. It is generally assumed that by 2 months of age adult-born neurons are mature and …

Various specialized structural/functional properties are considered essential for contextual
memory encoding by hippocampal mossy fiber (MF) synapses. Although investigated to …

How structural and functional properties of synapses relate to each other is a fundamental
question in neuroscience. Electrophysiology has elucidated mechanisms of synaptic …