Human protein kinase C (PKC) isoforms have been implicated in diseases such as
Alzheimer's, diabetes and cancers. In contrast to mammals, which have at least nine genes …

Cell-signaling pathways are essential for cells to respond and adapt to changes in their
environmental conditions. The cell-wall integrity (CWI) pathway of Saccharomyces …

The cell wall is an essential dynamic structure for shielding fungus from environmental
stress, and its synthesizing and remodeling are regulated by the cell wall integrity (CWI) …

Parkinson's disease (PD) is a neurodegenerative disease that occurs mostly in middle-aged
and older adults. Its main pathological feature is the progressive death of substantia nigra …

The protein kinase C (PKC) family plays important regulatory roles in numerous cellular
processes. Saccharomyces cerevisiae contains a single PKC, Pkc1, whereas in mammals …

Start is the main decision point in the eukaryotic cell cycle at which cells commit to a new
round of cell division. It involves the irreversible activation of a transcriptional programme …

How do boundaries between cells of different types form? Such boundaries are critical for
metazoan development, but even in microorganisms, boundaries between cells of different …