[HTML][HTML] A focus on yeast mating: From pheromone signaling to cell-cell fusion

B Sieber, JM Coronas-Serna, SG Martin - Seminars in cell & developmental …, 2023 - Elsevier
Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …

Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies

CJ Bashor, N Patel, S Choubey, A Beyzavi, J Kondev… - Science, 2019 - science.org
Eukaryotic genes are regulated by multivalent transcription factor complexes. Through
cooperative self-assembly, these complexes perform nonlinear regulatory operations …

Cellular heterogeneity: Yeast-side story

S Pinheiro, S Pandey, S Pelet - Fungal Biology Reviews, 2022 - Elsevier
A major challenge for cells lies in their ability to detect, respond and adapt to changing
environments that may threaten their survival. Among the numerous evolutionary strategies …

The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles

I Ensinck, A Maman, WS Albihlal, M Lassandro… - Elife, 2023 - elifesciences.org
Abstract N6-methyladenosine (m6A), the most abundant mRNA modification, is deposited in
mammals/insects/plants by m6A methyltransferase complexes (MTC) comprising a catalytic …

Cascaded amplifying circuit enables sensitive detection of fungal pathogens

C Fan, N He, J Yuan - Biosensors and Bioelectronics, 2024 - Elsevier
The rapid and accurate detection of fungal pathogens is of utmost importance in the fields of
healthcare, food safety, and environmental monitoring. In this study, we implemented a …

Oxidative stress stimulation leads to cell-specific oxidant and antioxidant responses in airway resident and inflammatory cells

HA Bilgic, B Kilic, BD Kockaya, BE Sarac, AK Suloglu… - Life sciences, 2023 - Elsevier
Aims The imbalance between reactive oxygen species (ROS) and the antioxidant response
has been linked to various airway diseases, including asthma. However, knowledge on cell …

Ratiometric GPCR signaling enables directional sensing in yeast

NT Henderson, M Pablo, D Ghose… - PLoS …, 2019 - journals.plos.org
Accurate detection of extracellular chemical gradients is essential for many cellular
behaviors. Gradient sensing is challenging for small cells, which can experience little …

Coupling cell communication and optogenetics: implementation of a light-inducible intercellular system in yeast

V Rojas, LF Larrondo - ACS Synthetic Biology, 2022 - ACS Publications
Cell communication is a widespread mechanism in biology, allowing the transmission of
information about environmental conditions. In order to understand how cell communication …

Trends & opportunities in visualization for physiology: A multiscale overview

LA Garrison, I Kolesar, I Viola, H Hauser… - Computer graphics …, 2022 - Wiley Online Library
Combining elements of biology, chemistry, physics, and medicine, the science of human
physiology is complex and multifaceted. In this report, we offer a broad and multiscale …

Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae

MR Clark-Cotton, NT Henderson, M Pablo… - Molecular biology of …, 2021 - Am Soc Cell Biol
Yeast decode pheromone gradients to locate mating partners, providing a model for
chemotropism. How yeast polarize toward a single partner in crowded environments is …