NJ Butcher, S Boukouvala, E Sim… - The pharmacogenomics …, 2002 - nature.com
The arylamine N-acetyltransferases (NATs) are involved in the metabolism of a variety of different compounds that we are exposed to on a daily basis. Many drugs and chemicals …
Compiling significant advances from more than a decade of research, this text presents breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …
Heterocyclic aromatic amines (HAAs) form during the high-temperature cooking of meats, poultry, and fish. Some HAAs also arise during the combustion of tobacco. HAAs are …
RJ Turesky, A Constable, J Richoz… - Chemical research in …, 1998 - ACS Publications
The dietary mutagens 2-amino-3, 8-dimethylimidazo [4, 5-f] quinoxaline (MeIQx) and 2- amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) are activated to genotoxins by rat …
RJ Turesky - Drug metabolism reviews, 2002 - Taylor & Francis
Heterocyclic aromatic amines (HAAs) are carcinogenic compounds formed in meats, fish, and poultry prepared under common household cooking practices. Some HAAs are also …
TT Mosby, M Cosgrove, S Sarkardei, KL Platt… - Anticancer …, 2012 - ar.iiarjournals.org
There is no doubt that diet is one of the main modifiable risk factors for many degenerative diseases, including cancer. More than 30% of adult cancers can be prevented or delayed by …
C Leuratti, MA Watson, EJ Deag, A Welch… - … Biomarkers & Prevention, 2002 - AACR
Colorectal biopsies from normal mucosa of participants in the United Kingdom Flexible Sigmoidoscopy Trial and European Prospective Investigation on Cancer (EPIC; n= 162) …
EL Jamin, A Riu, T Douki, L Debrauwer, JP Cravedi… - PLoS …, 2013 - journals.plos.org
Colorectal neoplasia is the third most common cancer worldwide. Environmental factors such as diet are known to be involved in the etiology of this cancer. Several epidemiological …
MQ McCreery, A Balmain - Annual Review of Cancer Biology, 2017 - annualreviews.org
Over a century has elapsed since the first demonstration that exposure to chemicals in coal tar can cause cancer in animals. These observations provided an essential causal …