The treatment of infected bone defects is a major clinical challenge, which requires the
development of scaffolds to simultaneously eliminate infection and provide a suitable …

Scaffold porosity is a critical factor in replicating the complex in vivo microenvironment,
directly influencing cellular interactions, migration, nutrient transfer, vascularization, and the …

The management and definitive treatment of segmental bone defects in the setting of acute
trauma, fracture non-union, revision joint arthroplasty, and tumor surgery are challenging …

The reconstruction of craniomaxillofacial bone defects remains clinically challenging. To
date, autogenous grafts are considered the gold standard but present critical drawbacks …

Osteoarthritis, a chronic, debilitating, and painful disease, is one of the leading causes of
disability and socioeconomic burden, with an estimated 250 million people affected …

Cardiovascular disease is a leading cause of morbidity. Current treatments include vessel
substitution using autologous/synthetic vascular grafts, but these commonly fail in small …

Three-dimensional (3D)-printed medical-grade polycaprolactone (mPCL) composite
scaffolds have been the first to enable the concept of scaffold-guided bone regeneration …

Extrusible biomaterials have recently attracted increasing attention due to the desirable
injectability and printability to allow minimally invasive administration and precise …

A fundamental outcome of bone tissue engineering is the regeneration of bone defects
presenting large dimensions. A promising solution in biomedical practice is the implantation …

Emerging additive manufacturing (AM) strategies can enable the engineering of hierarchal
scaffold structures for guiding tissue regeneration. Here, the advantages of two AM …