Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

While formation and regeneration of the skeleton have been studied for a long period of
time, significant scientific advances in this field continue to emerge based on an unmet …

Currently, healing of large bone defects faces significant challenges such as a bulk of bone
regeneration and revascularization on the bone defect region. Here, a “cell-free scaffold …

Background Mice are increasingly used in fracture healing research because of the
opportunity to use transgenic animals. While both, male and female mice are employed …

An estimated 100,000 patients each year in the United States suffer severe disability from
bone defects that fail to heal, a condition where bone-regenerative therapies could provide …

There is an unmet need for improved, clinically relevant methods to longitudinally quantify
bone healing during fracture care. Here we develop a smart bone plate to wirelessly monitor …

The Life of a Fracture: Biologic Progression, Healing Gone A... : JBJS Reviews The Life of a
Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union : JBJS …

Long bone fractures are one of the most common and costly medical conditions
encountered after trauma. Characterization of the biology of fracture healing and …

Background The aetiology of equine medial femoral condyle (MFC) subchondral bone
radiolucencies (SR) is unknown. Objectives Characterise the microstructural structural …

Introduction Endochondral ossification is a complex biological phenomenon involving a
variety of factors and cells. Cyclin-dependent kinase inhibitor 1 (p21) inhibits cell cycle …