The design of nanoparticles is critical for their efficient use in many applications ranging from
biomedicine to sensing and energy. While shape and size are responsible for the properties …

Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Peptide drugs hold great potential for the treatment of infectious diseases due to their
unconventional mechanisms of action, biocompatibility, biodegradability and ease of …

Bio-based nanomaterials have received considerable attention in cancer therapies due to
their potent characteristics such as autologous pharmaceutical, synergetic effects …

In the late 70's, the discovery of the restriction enzymes made possible the biological
production of functional proteins by recombinant DNA technologies, a fact that largely …

Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug …

Click chemistry has been proven to be very useful in drug delivery. Due to the availability of
a large number of click reactions with a various characteristics, selection of appropriate …

Proteins have the capacity to treat a multitude of diseases both as therapeutics and as drug
carriers due to their complex functional properties, specificity toward binding partners …

DNA Holliday junction (HJ) is a four-way stranded DNA intermediate that formed in
replication fork regression, homology-dependent repair and mitosis, performing a significant …

Ferroptosis and autophagy are the two forms of the regulation of cell death that play
important roles in cancer therapy. However, little is known about the combination of the …