Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV
E De Clercq - International journal of antimicrobial agents, 2009 - Elsevier
In 2008, 25 years after the human immunodeficiency virus (HIV) was discovered as the then
tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti …
tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti …
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989 …
MP de Béthune - Antiviral research, 2010 - Elsevier
It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …
Dolutegravir in antiretroviral-experienced patients with raltegravir-and/or elvitegravir-resistant HIV-1: 24-week results of the phase III VIKING-3 study
A Castagna, F Maggiolo, G Penco… - The Journal of …, 2014 - academic.oup.com
Abstract Background. The pilot phase IIb VIKING study suggested that dolutegravir (DTG), a
human immunodeficiency virus (HIV) integrase inhibitor (INI), would be efficacious in INI …
human immunodeficiency virus (HIV) integrase inhibitor (INI), would be efficacious in INI …
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society–USA panel
SM Hammer, JJ Eron, P Reiss, RT Schooley… - Jama, 2008 - jamanetwork.com
Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
Raltegravir with optimized background therapy for resistant HIV-1 infection
RT Steigbigel, DA Cooper, PN Kumar… - … England Journal of …, 2008 - Mass Medical Soc
Background Raltegravir (MK-0518) is an inhibitor of human immunodeficiency virus type 1
(HIV-1) integrase active against HIV-1 susceptible or resistant to older antiretroviral drugs …
(HIV-1) integrase active against HIV-1 susceptible or resistant to older antiretroviral drugs …
Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel
MS Hirsch, HF Günthard, JM Schapiro… - Clinical Infectious …, 2008 - academic.oup.com
Resistance to antiretroviral drugs remains an important limitation to successful human
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …
Non‐nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability
I Usach, V Melis, JE Peris - African Journal of Reproduction and …, 2013 - journals.lww.com
Introduction: Human immunodeficiency virus (HIV) type-1 non-nucleoside and nucleoside
reverse transcriptase inhibitors (NNRTIs) are key drugs of highly active antiretroviral therapy …
reverse transcriptase inhibitors (NNRTIs) are key drugs of highly active antiretroviral therapy …
[HTML][HTML] HIV-1 drug resistance mutations: an updated framework for the second decade of HAART
RW Shafer, JM Schapiro - AIDS reviews, 2008 - ncbi.nlm.nih.gov
More than 200 mutations are associated with antiretroviral resistance to drugs belonging to
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …
TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1
H Azijn, I Tirry, J Vingerhoets… - Antimicrobial agents …, 2010 - Am Soc Microbiol
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) have proven efficacy against
human immunodeficiency virus type 1 (HIV-1). However, in the setting of incomplete viral …
human immunodeficiency virus type 1 (HIV-1). However, in the setting of incomplete viral …
British HIV Association Guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008.
BG Gazzard - HIV medicine, 2008 - search.ebscohost.com
The article presents guidelines from the British HIV Association for the treatment of HIV-1-
infected adults using antiretroviral therapy. It presents data from clinical trials on the …
infected adults using antiretroviral therapy. It presents data from clinical trials on the …