Compounds with therapeutic potential against novel respiratory 2019 coronavirus

MA Martinez - Antimicrobial agents and chemotherapy, 2020 - Am Soc Microbiol
Currently, the expansion of the novel human respiratory coronavirus (known as SARS-CoV-
2 [severe acute respiratory syndrome coronavirus 2], COVID-2019 [coronavirus disease …

Antiviral approaches against influenza virus

R Kumari, SD Sharma, A Kumar, Z Ende… - Clinical microbiology …, 2023 - Am Soc Microbiol
Preventing and controlling influenza virus infection remains a global public health
challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are …

[HTML][HTML] Influenza antivirals and their role in pandemic preparedness

JC Jones, HL Yen, P Adams, K Armstrong… - Antiviral research, 2023 - Elsevier
Effective antivirals provide crucial benefits during the early phase of an influenza pandemic,
when vaccines are still being developed and manufactured. Currently, two classes of viral …

Advances in respiratory virus therapeutics–A meeting report from the 6th isirv Antiviral Group conference

JH Beigel, HH Nam, PL Adams, A Krafft, WL Ince… - Antiviral research, 2019 - Elsevier
Abstract The International Society for Influenza and other Respiratory Virus Diseases held its
6th Antiviral Group (isirv-AVG) conference in Rockville, Maryland, November 13–15, 2018 …

Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy

C Cruz-Teran, K Tiruthani, M McSweeney, A Ma… - Advanced drug delivery …, 2021 - Elsevier
To address the COVID-19 pandemic, there has been an unprecedented global effort to
advance potent neutralizing mAbs against SARS-CoV-2 as therapeutics. However, historical …

[HTML][HTML] Overview of current therapeutics and novel candidates against influenza, respiratory syncytial virus, and Middle East respiratory syndrome coronavirus …

MA Behzadi, VH Leyva-Grado - Frontiers in microbiology, 2019 - frontiersin.org
Emergence and re-emergence of respiratory virus infections represent a significant threat to
global public health, as they occur seasonally and less frequently (such as in the case of …

Broad-spectrum pan-genus and pan-family virus vaccines

CW Tan, SA Valkenburg, LLM Poon, LF Wang - Cell Host & Microbe, 2023 - cell.com
Although the development and clinical application of SARS-CoV-2 vaccines during the
COVID-19 pandemic demonstrated unprecedented vaccine success in a short time frame, it …

Controlled human infection models to accelerate vaccine development

RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

The current state of research on influenza antiviral drug development: drugs in clinical trial and licensed drugs

Y Li, S Huo, Z Yin, Z Tian, F Huang, P Liu, Y Liu, F Yu - Mbio, 2023 - Am Soc Microbiol
Influenza viruses (IVs) threaten global human health due to the high morbidity, infection, and
mortality rates. Currently, the influenza drugs recommended by the FDA are oseltamivir …

[HTML][HTML] Drugs for influenza treatment: is there significant news?

N Principi, B Camilloni, A Alunno, I Polinori… - Frontiers in …, 2019 - frontiersin.org
Vaccines remain the best measure to reduce total influenza burden. However, presently
available influenza vaccines have some limitations that cause a reduced efficacy compared …