Medicinal chemistry of acridine and its analogues
P Prasher, M Sharma - MedChemComm, 2018 - pubs.rsc.org
'Acridine'along with its functional analogue 'Acridone'is the most privileged pharmacophore
in medicinal chemistry with diverse applications ranging from DNA intercalators …
in medicinal chemistry with diverse applications ranging from DNA intercalators …
Synthesis of novel cytotoxic tetracyclic acridone derivatives and study of their molecular docking, ADMET, QSAR, bioactivity and protein binding properties
R Veligeti, RB Madhu, J Anireddy, VR Pasupuleti… - Scientific Reports, 2020 - nature.com
Acridone based synthetic and natural products with inherent anticancer activity advancing
the research and generating a large number of structurally diversified compounds. In this …
the research and generating a large number of structurally diversified compounds. In this …
Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents
D Song, N Zhang, P Zhang, N Zhang, W Chen… - European Journal of …, 2021 - Elsevier
With the increasing incidence of antibiotic resistance, new antibacterial agents having novel
mechanisms of action hence are in an urgent need to combat infectious diseases caused by …
mechanisms of action hence are in an urgent need to combat infectious diseases caused by …
Computational studies on acetylcholinesterase inhibitors: From biochemistry to chemistry
K Bagri, A Kumar, P Kumar - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
Acetylcholinesterase inhibitors are the most promising therapeutics for Alzheimer's disease
treatment as these prevent the loss of acetylcholine and slows the progression of the …
treatment as these prevent the loss of acetylcholine and slows the progression of the …
Novel thiazole‐piperazine derivatives as potential cholinesterase inhibitors
Ş Demirayak, Z Şahin, M Ertaş… - Journal of …, 2019 - Wiley Online Library
Dementia is a cognitive disorder mostly associated with Alzheimer's disease (AD) in addition
to being seen in many other diseases of the central nervous system (CNS). The limited …
to being seen in many other diseases of the central nervous system (CNS). The limited …
Synthesis, characterization, computational studies, antimicrobial activities and carbonic anhydrase inhibitor effects of 2-hydroxy acetophenone-N-methyl p …
Hydroxyacetophenone-N-methyl p-toluenesulfonylhydrazone (afptsmh) derived from p-
toluenesulfonicacid-1-methylhydrazide (ptsmh) and its Co (II), Pd (II), Pt (II) complexes were …
toluenesulfonicacid-1-methylhydrazide (ptsmh) and its Co (II), Pd (II), Pt (II) complexes were …
Index of ideality of correlation and correlation contradiction index: a confluent perusal on acetylcholinesterase inhibitors
K Bagri, A Kumar, M Nimbhal, P Kumar - Molecular Simulation, 2020 - Taylor & Francis
Alzheimer's disease is one of the leading causes of disability and death in the global
scenario. Acetylcholinesterase inhibitors are symptomatically involved in the therapeutic …
scenario. Acetylcholinesterase inhibitors are symptomatically involved in the therapeutic …
Nonstoichiometric Mesoporous Cu1.90S Nanoparticles Hydrothermally Prepared from a Copper Anthranilato Complex Inhibit Cellulases of Phytopathogenic Fungi
ABM Ibrahim, GAE Mahmoud - Journal of Inorganic and Organometallic …, 2019 - Springer
A copper sulfide precursor of the general formula Cu (C 13 H 9 O 2 NCl) 2 (H 2 O) 2 {C 13 H
9 O 2 NCl= 2-(2-chlorophenylamino) benzoate} was synthesized and routinely characterized …
9 O 2 NCl= 2-(2-chlorophenylamino) benzoate} was synthesized and routinely characterized …
Ultrasound irradiation of hydrothermally engineered sub-20 nm PbS nanoparticles and effect of their size on Aspergillus species morphology
GAE Mahmoud, ABM Ibrahim - Mendeleev Communications, 2024 - Elsevier
Lead sulfide nanoparticles were hydrothermally synthesized and their size was diminished
via exposure to ultrasound waves. Both h-PbS and h, us-PbS nanoparticles of different sizes …
via exposure to ultrasound waves. Both h-PbS and h, us-PbS nanoparticles of different sizes …
Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential …
GF Makhaeva, NV Kovaleva, EV Rudakova… - Frontiers in …, 2023 - frontiersin.org
We investigated the inhibitory activities of novel 9-phosphoryl-9, 10-dihydroacridines and 9-
phosphorylacridines against acetylcholinesterase (AChE), butyrylcholinesterase (BChE) …
phosphorylacridines against acetylcholinesterase (AChE), butyrylcholinesterase (BChE) …