Structure and function of KH domains
R Valverde, L Edwards, L Regan - The FEBS journal, 2008 - Wiley Online Library
The hnRNP K homology (KH) domain was first identified in the protein human
heterogeneous nuclear ribonucleoprotein K (hnRNP K) 14 years ago. Since then, KH …
heterogeneous nuclear ribonucleoprotein K (hnRNP K) 14 years ago. Since then, KH …
Selected glimpses into the activation and function of Src kinase
JD Bjorge, A Jakymiw, DJ Fujita - Oncogene, 2000 - nature.com
Since the discovery of the v-src and c-src genes and their products, much progress has been
made in the elucidation of the structure, regulation, localization, and function of the Src …
made in the elucidation of the structure, regulation, localization, and function of the Src …
STAR, a gene family involved in signal transduction and activation of RNA
C Vernet, K Artzt - Trends in Genetics, 1997 - cell.com
A new subfamily of KH-domain-containing RNA-binding proteins is encoded by genes that
are conserved from yeast to humans. Mutations with interesting developmental phenotypes …
are conserved from yeast to humans. Mutations with interesting developmental phenotypes …
Sam68 RNA Binding Protein Is an In Vivo Substrate for Protein Arginine N-Methyltransferase 1
J Coˆté, FM Boisvert, MC Boulanger… - Molecular biology of …, 2003 - Am Soc Cell Biol
RNA binding proteins often contain multiple arginine glycine repeats, a sequence that is
frequently methylated by protein arginine methyltransferases. The role of this …
frequently methylated by protein arginine methyltransferases. The role of this …
Sam68, the KH domain-containing superSTAR
Sam68 is one of the most studied members of the STAR family of RNA-binding proteins
since its identification over a decade ago. Since its ascension into prominence, enormous …
since its identification over a decade ago. Since its ascension into prominence, enormous …
KH–RNA interactions: back in the groove
G Nicastro, IA Taylor, A Ramos - Current opinion in structural biology, 2015 - Elsevier
Highlights•KH domain specific recognition of G-rich sequences.•STAR domain dimerisation
and RNA recognition.•KH di-domains as architectural factors.The hnRNP K-homology (KH) …
and RNA recognition.•KH di-domains as architectural factors.The hnRNP K-homology (KH) …
Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains
Src homology 3 (SH3) and WW domains are known to associate with proline-rich motifs
within their respective ligands. Here we demonstrate that the proposed adapter protein for …
within their respective ligands. Here we demonstrate that the proposed adapter protein for …
The Interaction and Colocalization of Sam68 with the Splicing-associated Factor YT521-B in Nuclear Dots Is Regulated by the Src Family Kinase p59fyn
AM Hartmann, O Nayler, FW Schwaiger… - Molecular biology of …, 1999 - Am Soc Cell Biol
Alternative pre-mRNA splicing patterns can change an extracellular stimulus, but the
signaling pathways leading to these changes are still poorly characterized. Here, we …
signaling pathways leading to these changes are still poorly characterized. Here, we …
The RNA-binding protein Sam68 is a multifunctional player in human cancer
P Bielli, R Busà, MP Paronetto… - Endocrine-related …, 2011 - erc.bioscientifica.com
Resistance to chemotherapy is a major complication in the treatment of advanced breast
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer …
[HTML][HTML] The STAR protein, GLD‐1, is a translational regulator of sexual identity in Caenorhabditis elegans
E Jan, CK Motzny, LE Graves, EB Goodwin - The EMBO Journal, 1999 - embopress.org
The Caenorhabditis elegans sex determination gene, tra‐2, is translationally regulated by
elements in the 3′‐untranslated region called TGEs. TGEs govern the translation of …
elements in the 3′‐untranslated region called TGEs. TGEs govern the translation of …