In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents
the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet …

Platelets play a fundamental role in normal hemostasis, while their inherited or acquired
dysfunctions are involved in a variety of bleeding disorders or thrombotic events. Several …

Light transmission aggregometry (LTA), which was independently developed in 1962 by
Born 1 and O'Brien 2, is considered the gold standard for testing platelet function, because it …

The guideline writing group was selected to be representative of UK‐based medical experts.
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …

Patients with cirrhosis develop complex alterations in primary hemostasis that include both
hypocoagulable and hypercoagulable features. This includes thrombocytopenia, multiple …

Platelet function testing is important for the diagnostic evaluation of common and rare
bleeding disorders. Our study goals were to promote best practices and reduce unnecessary …

Background: Light transmission aggregometry (LTA) is the most common method used in
clinical and research laboratories to assess platelet function. However, the method has …

The contribution of platelets to normal hemostasis and vascular disease is well described.
However, recent studies make it clear that much remains to be learned about platelet …

Background: Variation in platelet reactivity contributes to disorders of hemostasis and
thrombosis, but the molecular mechanisms are not well understood. Objectives: To discover …

Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …