Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberine is a natural pentacyclic isoquinoline alkaloid that has been isolated as the
principal component of many popular medicinal plants such as the genus Berberis, Coptis …

Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

Neurodegenerative diseases (NDs) are characterized by disorders with progressive
deterioration of the structure and/or function of neurons. Genetic mutations can lead to many …

Neurodegenerative diseases (NDDs) are conditions that cause neuron structure and/or
function to deteriorate over time. Genetic alterations may be responsible for several NDDs …

Traditionally, herbal compounds have been the focus of scientific interest for the last several
centuries, and continuous research into their medicinal potential is underway. Berberine …

Neurodegenerative diseases are normally distinguished as disorders with loss of neurons.
Various compounds are being tested to treat neurodegenerative diseases (NDs) but they …

Background Alzheimer's diseases (AD) and dementia are among the highly prevalent
neurological disorders characterized by deposition of beta amyloid (Aβ) plaques, dense …

Renal ischemia/reperfusion (I/R) injury following kidney transplantation has been found to
be a great clinical problem owing to initiation of acute inflammatory responses and …