Long noncoding RNAs in the pathogenesis of insulin resistance

W Yang, Y Lyu, R Xiang, J Yang - International journal of molecular …, 2022 - mdpi.com
Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …

[HTML][HTML] Activation of sphingosine-1-phosphate receptor 2 (S1PR2) upregulates dihydropyrimidine dehydrogenase (DPD) expression in colon cancer cells

ZK Guo, XF Wu, MY Tan, WS Liang, YM Yang… - Journal of Advanced …, 2025 - Elsevier
Introduction Dihydropyrimidine dehydrogenase (DPD) is a major determinant of cancer 5-
fluorouracyl (5-FU) resistance via its direct degradation. However, the mechanisms of …

A CpG island promoter drives the CXXC5 gene expression

P Yaşar, G Kars, K Yavuz, G Ayaz, Ç Oğuztüzün… - Scientific Reports, 2021 - nature.com
CXXC5 is a member of the zinc-finger CXXC family that binds to unmethylated CpG
dinucleotides. CXXC5 modulates gene expressions resulting in diverse cellular events …

Long-term severe hypoxia adaptation induces non-canonical EMT and a novel Wilms Tumor 1 (WT1) isoform

J Quenneville, A Feghaly, M Tual, K Thomas… - Cancer Gene …, 2024 - nature.com
The majority of cancer deaths are caused by solid tumors, where the four most prevalent
cancers (breast, lung, colorectal and prostate) account for more than 60% of all cases (1) …