Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Small-molecule two-photon probes for bioimaging applications

HM Kim, BR Cho - Chemical reviews, 2015 - ACS Publications
Small-molecule fluorescent probes are attractive and versatile materials for studying
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes

X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease

L Gao, W Wang, X Wang, F Yang, L Xie… - Chemical Society …, 2021 - pubs.rsc.org
Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

π-Expanded coumarins: synthesis, optical properties and applications

M Tasior, D Kim, S Singha, M Krzeszewski… - Journal of Materials …, 2015 - pubs.rsc.org
Coumarins fused with other aromatic units have recently emerged as a hot topic of research.
Their synthesis is partly based on classical methodologies such as Pechmann reaction or …

Addressing the autofluorescence issue in deep tissue imaging by two-photon microscopy: the significance of far-red emitting dyes

YW Jun, HR Kim, YJ Reo, M Dai, KH Ahn - Chemical science, 2017 - pubs.rsc.org
The fluorescence imaging of tissue is essential for studying biological events beyond the
cellular level. Two-photon microscopy based on the nonlinear light absorption of fluorescent …

Hydrazine exposé: the next-generation fluorescent probe

Y Jung, IG Ju, YH Choe, Y Kim, S Park, YM Hyun… - ACS …, 2019 - ACS Publications
Hydrazine (N2H4) is one of the most important pnictogen hydride chemicals, and is utilized
within a wide spectrum of industries. As a result of its extensive use, hydrazine's monitoring …

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background …

D Kim, H Moon, SH Baik, S Singha… - Journal of the …, 2015 - ACS Publications
Fluorescence imaging of tissues offer an essential means for studying biological systems.
Autofluorescence becomes a serious issue in tissue imaging under excitation at UV–vis …

An endeavor in the reaction-based approach to fluorescent probes for biorelevant analytes: challenges and achievements

S Singha, YW Jun, S Sarkar… - Accounts of chemical …, 2019 - ACS Publications
Conspectus The promising features of fluorescence spectroscopy have inspired a quest for
fluorescent probes for analysis and monitoring of molecular interactions in biochemical …

A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models

L Li, CW Zhang, GYJ Chen, B Zhu, C Chai… - Nature …, 2014 - nature.com
The unusually high MAO-B activity consistently observed in Parkinson's disease (PD)
patients has been proposed as a biomarker; however, this has not been realized due to the …